The experimental production of krimpsiekte in sheep with Tylecodon grandiflorus (Burm.f.) Toelken and some of its bufadienolides.
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Date
Authors
Anderson, L.A.P.
Joubert, J.P.J.
Kellerman, T. Stephanus
Schultz, R.A. (Rowena Anitra)
Procos, J.
Olivier, Philippa M.
Journal Title
Journal ISSN
Volume Title
Publisher
Published by The Government Printer, Pretoria
Abstract
Six bufadienolides were isolated from Tylecodon grandiflorus (Burm. f.) Toelken. The paretic syndrome, krimpsiekte, could be induced in sheep either by repeated oral administration of small quantities of plant material or the intravenous injection of small quantities of certain bufadienolides. A mild to moderate, acute to subacute, multifocal cardiomyopathy was evident in sheep poisoned by both the plant and the bufadienolides.
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Keywords
Veterinary medicine
Sustainable Development Goals
Citation
Anderson, LAP, Joubert, JPJ, Prozesky, L, Kellerman, TS, Schultz, RA, Procos, J & Olivier, PM 1983, 'The experimental production of krimpsiekte in sheep with Tylecodon grandiflorus (Burm.f.) Toelken and some of its bufadienolides’, Onderstepoort Journal of Veterinary Research, vol. 50, no. 4, pp. 301-307.