Use of hyphenated analytical techniques to identify the bioactive constituents of Gunnera perpensa L., a South African medicinal plant, which potently inhibit SARS-CoV-2 spike glycoprotein-host ACE2 binding

dc.contributor.authorInvernizzi, Luke
dc.contributor.authorMoyo, Phanankosi
dc.contributor.authorCassel, Joel
dc.contributor.authorIsaacs, Freddie J.
dc.contributor.authorSalvino, Joseph M.
dc.contributor.authorMontaner, Luis J.
dc.contributor.authorTietjen, Ian
dc.contributor.authorMaharaj, Vinesh J.
dc.contributor.emailvinesh.maharaj@up.ac.zaen_US
dc.date.accessioned2023-05-26T09:34:32Z
dc.date.available2023-05-26T09:34:32Z
dc.date.issued2022-04
dc.description.abstractPlease read abstract in the article.en_US
dc.description.departmentChemistryen_US
dc.description.librarianhj2023en_US
dc.description.sponsorshipThe DSI (Department of Science and Innovation Agency of South Africa); the NRF (National Research Foundation); the Wistar Science Discovery Fund; the Commonwealth of Pennsylvania; the Canadian Institutes for Health Research; the Robert I. Jacobs Fund of the Philadelphia Foundation and the Herbert Kean, M.D., Family Professorship.en_US
dc.description.urihttps://link.springer.com/journal/216en_US
dc.identifier.citationInvernizzi, L., Moyo, P., Cassel, J. et al. Use of hyphenated analytical techniques to identify the bioactive constituents of Gunnera perpensa L., a South African medicinal plant, which potently inhibit SARS-CoV-2 spike glycoprotein–host ACE2 binding. Analytical and Bioanalytical Chemistry 414, 3971–3985 (2022). https://doi.org/10.1007/s00216-022-04041-3.en_US
dc.identifier.issn1618-2642 (print)
dc.identifier.issn1618-2650 (online)
dc.identifier.other10.1007/s00216-022-04041-3
dc.identifier.urihttp://hdl.handle.net/2263/90814
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.rights© Springer-Verlag GmbH Germany, part of Springer Nature 2022. The original publication is available at : http://link.springer.com/journal/216.en_US
dc.subjectCOVID-19 pandemicen_US
dc.subjectSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)en_US
dc.subjectCoronavirus disease 2019 (COVID-19)en_US
dc.subjectGunnera perpensaen_US
dc.subjectUPLC-IMS-HRMSen_US
dc.subjectAntiviral treatmenten_US
dc.subjectPunicalinen_US
dc.subjectPunicalaginen_US
dc.titleUse of hyphenated analytical techniques to identify the bioactive constituents of Gunnera perpensa L., a South African medicinal plant, which potently inhibit SARS-CoV-2 spike glycoprotein-host ACE2 bindingen_US
dc.typePostprint Articleen_US

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