Use of hyphenated analytical techniques to identify the bioactive constituents of Gunnera perpensa L., a South African medicinal plant, which potently inhibit SARS-CoV-2 spike glycoprotein-host ACE2 binding
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Date
Authors
Invernizzi, Luke
Moyo, Phanankosi
Cassel, Joel
Isaacs, Freddie J.
Salvino, Joseph M.
Montaner, Luis J.
Tietjen, Ian
Maharaj, Vinesh J.
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Publisher
Springer
Abstract
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Keywords
COVID-19 pandemic, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Coronavirus disease 2019 (COVID-19), Gunnera perpensa, UPLC-IMS-HRMS, Antiviral treatment, Punicalin, Punicalagin
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Citation
Invernizzi, L., Moyo, P., Cassel, J. et al. Use of hyphenated analytical techniques to identify the bioactive constituents of Gunnera perpensa L., a South African medicinal plant, which potently inhibit SARS-CoV-2 spike glycoprotein–host ACE2 binding. Analytical and Bioanalytical Chemistry 414, 3971–3985 (2022). https://doi.org/10.1007/s00216-022-04041-3.