Asthma treatment in children : a pragmatic approach

dc.contributor.authorMasekela, Refiloe
dc.contributor.authorJeevarathnum, A.C.
dc.contributor.authorKling, S.
dc.contributor.authorGray, T.C.
dc.contributor.authorMorrison, J.
dc.contributor.authorVanker, A.
dc.contributor.authorPuterman, A.S.
dc.contributor.authorRhode, D.
dc.contributor.authorZollner, E.W.
dc.contributor.authorDe Waal, P.
dc.contributor.authorManjra, Ahmed I.
dc.contributor.authorLevin, M.
dc.contributor.authorZar, Heather J.
dc.contributor.authorGreen, Robin J.
dc.contributor.authorKritzinger, F.E.
dc.date.accessioned2018-11-29T04:50:09Z
dc.date.available2018-11-29T04:50:09Z
dc.date.issued2018-08
dc.description.abstractBACKGROUND. Asthma is a heterogeneous condition characterised by chronic inflammation and variable expiratory airflow limitation, with airway reversibility. Management of chronic inflammation with anti-asthma medication improves asthma control and quality of life. OBJECTIVES. To provide an evidence-based approach for chronic asthma management in young children and adolescents and provide guidance on the use of new asthma drugs in children. METHODS. The South African Childhood Asthma Working Group (SACAWG) convened in January 2017. The asthma treatment task group reviewed the available scientific literature and international asthma treatment guidelines. The evidence was then graded according to the Grades of Recommendation Assessment, Development and Evaluation (GRADE) system and recommendations were made based on scientific evidence and local context. Asthma management recommendations were made for children ˂6 years of age and older children and adolescents, as well as for stepping up and stepping down of therapy. This review does not include biologics or novel asthma drugs, which are covered in another CME article in this edition of SAMJ. CONCLUSIONS. To ensure good response, treatment and adherence, type of medication, device and checking of technique are all critical. Stepping up of therapy should be done only after ensuring good adherence and technique. Once therapeutic response is achieved, medication administration has to be stepped down to improve ease of use and avoid unnecessary side-effects.en_ZA
dc.description.departmentPaediatrics and Child Healthen_ZA
dc.description.librarianam2018en_ZA
dc.description.sponsorshipSACAWG conducted a workshop that received an unconditional educational grant from the Allergy Society of South Africa – funded by Novartis.en_ZA
dc.description.urihttp://www.samj.org.zaen_ZA
dc.identifier.citationMasekela, R., Jeevanathrum, A., Kling, S. et al. 2018, 'Asthma treatment in children : a pragmatic approach', South African Medical Journal, vol. 108, no. 8, pp. 612-618.en_ZA
dc.identifier.issn0256-9574 (print)
dc.identifier.issn2078-5135 (online)
dc.identifier.other10.7196/SAMJ.2018.v108i8.13164
dc.identifier.urihttp://hdl.handle.net/2263/67391
dc.language.isoenen_ZA
dc.publisherHealth and Medical Publishing Groupen_ZA
dc.rights© 2018, South African Medical Association. This article is licensed under a Creative Commons Attribution-NonCommercial Works License (CC BY-NC 3.0).en_ZA
dc.subjectAsthmaen_ZA
dc.subjectChronic inflammationen_ZA
dc.subjectRandomized controlled trialen_ZA
dc.subjectDose inhaled budesonideen_ZA
dc.subjectLeukotriene receptor antagonisten_ZA
dc.subjectSeasonal allergic rhinitisen_ZA
dc.subjectMild persistent asthmaen_ZA
dc.subjectChildhood asthmaen_ZA
dc.subjectMontelukasten_ZA
dc.subjectCorticosteroidsen_ZA
dc.subjectSouth African Childhood Asthma Working Group (SACAWG)en_ZA
dc.subjectGrades of recommendation assessment, development and evaluation (GRADE)en_ZA
dc.titleAsthma treatment in children : a pragmatic approachen_ZA
dc.typeArticleen_ZA

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