In silico docking and ADMET studies on clinical targets for type 2 diabetes correlated to in vitro inhibition of pancreatic alpha-amylase and alpha-glucosidase by rutin, caffeic acid, p-coumaric acid, and vanillin

dc.contributor.authorMcmillan, Jamie
dc.contributor.authorBester, Megan Jean
dc.contributor.authorApostolides, Zeno
dc.contributor.emailu16016760@tuks.co.za
dc.date.accessioned2025-07-31T12:57:50Z
dc.date.issued2025-03
dc.descriptionDATA AVAILABILITY : No datasets were generated or analysed during the current study.
dc.description.abstractPlease read abstract in the article.
dc.description.departmentBiochemistry, Genetics and Microbiology (BGM)
dc.description.departmentAnatomy
dc.description.embargo2026-03-14
dc.description.librarianhj2025
dc.description.sdgSDG-03: Good health and well-being
dc.description.urihttps://link.springer.com/journal/40203
dc.identifier.citationMcMillan, J., Bester, M.J. & Apostolides, Z. In silico docking and ADMET studies on clinical targets for type 2 diabetes correlated to in vitro inhibition of pancreatic alpha-amylase and alpha-glucosidase by rutin, caffeic acid, p-coumaric acid, and vanillin. In Silico Pharmacology 13, 42 (2025). https://doi.org/10.1007/s40203-025-00324-6.
dc.identifier.issn2193-9616 (online)
dc.identifier.other10.1007/s40203-025-00324-6
dc.identifier.urihttp://hdl.handle.net/2263/103732
dc.language.isoen
dc.publisherSpringer
dc.rights© The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2025. The original publication is available at : https://link.springer.com/journal/40203.
dc.subjectAlpha-glucosidase
dc.subjectCaco2 cytotoxicity
dc.subjectMolecular docking
dc.subjectMolecular dynamics
dc.subjectInhibition constant
dc.subjectPancreatic alpha-amylase
dc.titleIn silico docking and ADMET studies on clinical targets for type 2 diabetes correlated to in vitro inhibition of pancreatic alpha-amylase and alpha-glucosidase by rutin, caffeic acid, p-coumaric acid, and vanillin
dc.typePostprint Article

Files

License bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Research Articles (Biochemistry, Genetics and Microbiology (BGM))
Research Articles (Anatomy)
Research Articles (University of Pretoria)
Simple item page