Successful treatment of disabling paroxysmal nonkinesigenic dyskinesia with deep brain stimulation of the globus pallidus internus

dc.contributor.authorVan Coller, Riaan
dc.contributor.authorSlabbert, Pieter
dc.contributor.authorSchutte, Clara-Maria
dc.date.accessioned2015-08-19T06:11:34Z
dc.date.available2015-08-19T06:11:34Z
dc.date.issued2014-10
dc.description.abstractParoxysmal nonkinesigenic dyskinesia (PNKD) causes episodes of treatment-resistant involuntary movements. Previous case reports showed effective treatment of PNKD with deep brain stimulation (DBS). We report 2 patients in whom DBS was highly successful when other treatment modalities had failed. METHODS : Two patients aged 34 and 24 years with a longstanding history of PNKD were treated with globus pallidus internus (GPi) DBS. Motor effects were monitored and followed up postoperatively and again at 6 months after surgery. RESULTS : Both patients responded very well to GPi DBS with complete suppression of dyskinesia after surgery in 1 patient and in the second after an additional adjustment of stimulation. CONCLUSION : GPi DBS might be an effective alternative treatment modality for PNKDen_ZA
dc.description.librarianhb2015en_ZA
dc.description.urihttp://www.karger.com/Journal/Home/224132en_ZA
dc.identifier.citationVan Coller, R, Slabbert, P, Vaidyanathan, J & Schutte, C 2014, 'Successful treatment of disabling paroxysmal nonkinesigenic dyskinesia with deep brain stimulation of the globus pallidus internus', Stereotactic and Functional Neurosurgery, vol. 92, no. 6, pp. 388-392.en_ZA
dc.identifier.issn1011-6125 (print)
dc.identifier.issn1423-0372 (online)
dc.identifier.other10.1159/000365226
dc.identifier.urihttp://hdl.handle.net/2263/49377
dc.language.isoenen_ZA
dc.publisherKargeren_ZA
dc.rights© 2014 S. Karger AG, Baselen_ZA
dc.subjectParoxysmal dyskinesiaen_ZA
dc.subjectParoxysmal nonkinesigenic dyskinesia (PNKD)en_ZA
dc.subjectDeep brain stimulation (DBS)en_ZA
dc.subjectGlobus pallidus internus (GPi)en_ZA
dc.titleSuccessful treatment of disabling paroxysmal nonkinesigenic dyskinesia with deep brain stimulation of the globus pallidus internusen_ZA
dc.typePostprint Articleen_ZA

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