Reporting incidences of neuroblastoma in various resource settings

dc.contributor.authorVan Heerden, Jaques
dc.contributor.authorAbraham, Natasha
dc.contributor.authorSchoeman, Judy
dc.contributor.authorReynders, David
dc.contributor.authorSingh, Elvira
dc.contributor.authorKruger, Mariana
dc.date.accessioned2022-04-29T08:17:51Z
dc.date.available2022-04-29T08:17:51Z
dc.date.issued2021-06-17
dc.description.abstractPURPOSE : The incidences of neuroblastoma (NB) differ significantly between various resource settings because of varying quality of cancer registries and underdiagnoses. This study aimed to evaluate current regional variations as reported by international cancer registries and the theoretical and reported differences in international NB incidences and to evaluate South Africa (SA) as a case for variable reporting. METHODS : A comprehensive literature review on registries reporting on NB was performed to construct incidence tables. The SEER Program incidence of 10.5/million children was used to calculate the expected number of NB cases for each country. Registry data of NB cases between 2000 and 2016 were requested from The South African National Cancer registry (SA-NCR) and the South African Children’s Tumour Registry (SACTR) for comparison and to perform a probabilistic linkage study. RESULTS : Internationally, incidences varied between –97.1% and +80% compared with the SEER program. SA under-reported NB cases by an estimated 74.2%. Between 2000 and 2016, the SA-NCR reported between 23 and 51 cases/year, whereas the SACTR reported between 18 and 57 cases/year for the same period. The incidence reported by the SA-NCR varied between 1.5 and 2.8/million children under 15-year per year, whereas the SACTR reported 1.74-2.6 cases/million children. Both registries reported incidences less than high-income country. A probabilistic record linkage of the two registries resulted in a combined incidence of 2.9 cases/million children. CONCLUSION : As with most low- and middle-income countries, SA has either a lower incidence or underdiagnoses of NB cases. The reasons for under-reporting are not clear, but can be due to undiagnosed NB cases with spontaneous regression, missed possible cases because of lack of autopsies, and diagnosed cases not recorded in registries.en_US
dc.description.departmentPaediatrics and Child Healthen_US
dc.description.librarianam2022en_US
dc.description.urihttp://ascopubs.org/journal/goen_US
dc.identifier.citationVan Heerden, J., Abraham, N., Schoeman, J. et al. 2021, 'Reporting incidences of neuroblastoma in various resource settings', JCO Global Oncology, vol. 7, pp. 947-964.en_US
dc.identifier.issn2687-8941
dc.identifier.other10.1200/GO.21.00054
dc.identifier.urihttps://repository.up.ac.za/handle/2263/84971
dc.language.isoenen_US
dc.publisherAmerican Society of Clinical Oncologyen_US
dc.rights© 2021 by American Society of Clinical Oncology. Creative Commons Attribution Non-Commercial No Derivatives 4.0 License.en_US
dc.subjectNeuroblastomaen_US
dc.subjectCanceren_US
dc.subjectSEER Programen_US
dc.subjectSouth Africa (SA)en_US
dc.subjectInternational cancer registriesen_US
dc.titleReporting incidences of neuroblastoma in various resource settingsen_US
dc.typeArticleen_US

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
VanHeerden_Reporting_2021.pdf
Size:
731.56 KB
Format:
Adobe Portable Document Format
Description:
Article

License bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
license.txt
Size:
1.75 KB
Format:
Item-specific license agreed upon to submission
Description: