Genome sequences of the 15 bluetongue virus vaccine strains incorporated in the South African live-attenuated vaccine

dc.contributor.authorMlingo, Tendai A.M.
dc.contributor.authorBeeton-Kempen, Natasha
dc.contributor.authorNthangeni, M. Bethuel
dc.contributor.authorTheron, Jacques
dc.contributor.authorMokoena, Nobalanda B.
dc.date.accessioned2025-02-12T13:05:57Z
dc.date.available2025-02-12T13:05:57Z
dc.date.issued2024-06
dc.descriptionDATA AVAILABILITY : The raw sequence data as well as assembled sequence data of the 15 serotypes were deposited in GenBank under BioProject number PRJNA718723. The accession numbers are summarised in Table 1. Detailed information on the sequencing data generated for each serotype such as nucleotide identity and the South African reference strain applied is available in Table S1 in figshare (https://doi.org/10.6084/m9.figshare.25611486 25611486).en_US
dc.description.abstractBluetongue disease in endemic areas is predominantly controlled through vaccination with live-attenuated vaccines. Sequencing of the original master seed viruses used in the production of Onderstepoort Biological Products vaccine was conducted. Nucleotide identities of 82.97%–100% were obtained for all sequences when compared to South African reference strains.en_US
dc.description.departmentBiochemistry, Genetics and Microbiology (BGM)en_US
dc.description.librarianam2024en_US
dc.description.sdgSDG-03:Good heatlh and well-beingen_US
dc.description.sponsorshipOnderstepoort Biological Products, the University of Pretoria (Faculty of Natural and Agricultural Sciences), and the Chemical Industries Education and Training Authority.en_US
dc.description.urihttps://journals.asm.org/journal/mraen_US
dc.identifier.citationMlingo, T.A.M., Beeton-Kempen, N., Nthangeni, M.B. et al. 2024, 'Genome sequences of the 15 bluetongue virus vaccine strains incorporated in the South African live-attenuated vaccine', Microbiology Resource Announcements, vol. 13, no. 6, pp. 1-4. DOI: 10.1128/mra.00223-24.en_US
dc.identifier.issn2576-098X
dc.identifier.other10.1128/mra.00223-24
dc.identifier.urihttp://hdl.handle.net/2263/100789
dc.language.isoenen_US
dc.publisherAmerican Society for Microbiologyen_US
dc.rights© 2024 Mlingo et al. This is an openaccess article distributed under the terms of the Creative Commons Attribution 4.0 International license.en_US
dc.subjectVaccinesen_US
dc.subjectLive-attenuateden_US
dc.subjectBluetongue virusen_US
dc.subjectBluetongue virus (BTV)en_US
dc.subjectSDG-03: Good health and well-beingen_US
dc.titleGenome sequences of the 15 bluetongue virus vaccine strains incorporated in the South African live-attenuated vaccineen_US
dc.typeArticleen_US

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