Genome sequences of the 15 bluetongue virus vaccine strains incorporated in the South African live-attenuated vaccine

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Authors

Mlingo, Tendai A.M.
Beeton-Kempen, Natasha
Nthangeni, M. Bethuel
Theron, Jacques
Mokoena, Nobalanda B.

Journal Title

Journal ISSN

Volume Title

Publisher

American Society for Microbiology

Abstract

Bluetongue disease in endemic areas is predominantly controlled through vaccination with live-attenuated vaccines. Sequencing of the original master seed viruses used in the production of Onderstepoort Biological Products vaccine was conducted. Nucleotide identities of 82.97%–100% were obtained for all sequences when compared to South African reference strains.

Description

DATA AVAILABILITY : The raw sequence data as well as assembled sequence data of the 15 serotypes were deposited in GenBank under BioProject number PRJNA718723. The accession numbers are summarised in Table 1. Detailed information on the sequencing data generated for each serotype such as nucleotide identity and the South African reference strain applied is available in Table S1 in figshare (https://doi.org/10.6084/m9.figshare.25611486 25611486).

Keywords

Vaccines, Live-attenuated, Bluetongue virus, Bluetongue virus (BTV), SDG-03: Good health and well-being

Sustainable Development Goals

SDG-03:Good heatlh and well-being

Citation

Mlingo, T.A.M., Beeton-Kempen, N., Nthangeni, M.B. et al. 2024, 'Genome sequences of the 15 bluetongue virus vaccine strains incorporated in the South African live-attenuated vaccine', Microbiology Resource Announcements, vol. 13, no. 6, pp. 1-4. DOI: 10.1128/mra.00223-24.