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The dataset for the inflammatory response during experimental infection and treatment of dogs with Babesia rossi

dc.contributor.authorAtkinson, Brogan Kim
dc.contributor.authorThompson, P.N. (Peter N.)
dc.contributor.authorVan Zyl, Estee
dc.contributor.authorGoddard, Amelia
dc.contributor.authorRautenbach, Yolandi
dc.contributor.authorSchoeman, Johan P.
dc.contributor.authorMukorera, Varaidzo
dc.contributor.authorLeisewitz, Andrew L.
dc.contributor.emailu27102093@tuks.co.zaen_US
dc.date.accessioned2022-11-02T05:56:24Z
dc.date.available2022-11-02T05:56:24Z
dc.date.issued2022-07-19
dc.description.abstractBabesia rossi causes severe morbidity and mortality in dogs in sub-Saharan Africa. This was an experimental study designed to observe systemic changes caused by Babesia rossi infection within a canine disease model as well as investigate the influence of inoculum dose and treatment on the progression of inflammation and clinical disease. Six healthy male beagle dogs formed the study population, one dog was splenectomised and used to raise the infectious inoculum, three were administered a high B. rossi infectious dose and two a low infectious dose. Clinical examination, complete blood count (CBC) and C-reactive protein (CRP) were determined daily. Cytokines were quantified on stored plasma collected during the study, using a canine specific cytokine magnetic bead panel (Milliplex©). The experiment was terminated, and treatment administered once predetermined experimental or humane endpoints were reached. The data and information provided in the following article is the summary of all dataen_US
dc.description.departmentCompanion Animal Clinical Studiesen_US
dc.description.departmentProduction Animal Studiesen_US
dc.description.librariandm2022en_US
dc.description.sponsorshipThe National Research Foundation.en_US
dc.description.urihttps://www.journals.elsevier.com/data-in-brief/en_US
dc.identifier.citationBrogan Kim Atkinson, Peter Thompson, Estee Van Zyl, Amelia Goddard, Yolandi Rautenbach, Johan Petrus Schoeman, Varaidzo Mukorera, Andrew Leisewitz, The dataset for the inflammatory response during experimental infection and treatment of dogs with Babesia rossi, Data in Brief, Volume 45, 2022, ISSN 2352-3409, https://doi.org/10.1016/j.dib.2022.108475.en_US
dc.identifier.issn2352-3409 (online)
dc.identifier.other10.1016/j.dib.2022.108475
dc.identifier.urihttps://repository.up.ac.za/handle/2263/88078
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.rights© 2022 Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).en_US
dc.subjectCytokinesen_US
dc.subjectC-reactive proteinen_US
dc.subjectLeukocytesen_US
dc.subjectTreatmenten_US
dc.subjectParasitemiaen_US
dc.subjectAnaemiaen_US
dc.subjectBabesia rossien_US
dc.titleThe dataset for the inflammatory response during experimental infection and treatment of dogs with Babesia rossien_US
dc.typeArticleen_US

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