Clinicoradiologic features of ameloblastomas : a single-centre study of 155 cases

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dc.contributor.author Smit, Chane
dc.contributor.author Robinson, Liam
dc.contributor.author Ker-Fox, Jason
dc.contributor.author Fonseca, Felipe Paiva
dc.contributor.author Van Heerden, Willem Francois Petrus
dc.contributor.author Uys, Andre
dc.date.accessioned 2024-08-07T07:56:50Z
dc.date.available 2024-08-07T07:56:50Z
dc.date.issued 2024-02
dc.description DATA AVAILABILITY STATEMENT : The data of the current study are summarised in the tables and supplementary tables. Access to raw data is subject to approval by the University of Pretoria, Faculty of Health Sciences Research Ethics Committee. en_US
dc.description SUPPLEMENTARY TABLES : TABLE S1. Summarised location of ABs (children vs. adults). TABLE S2. Summarised radiological features of ABs (adults vs. children). en_US
dc.description.abstract BACKGROUND : The purpose of the current study was to report on the clinical presentation and radiologic features of 155 cases of ameloblastoma (AB), representing a detailed, large, single-centre radiologic study. METHODS : Histologically confirmed cases were reviewed over 11 years. Demographic and clinical data were retrieved from the patient's records. Radiologic information was analysed from available radiographs. The radiologic features of ABs were assessed according to the mean age of presentation and the mean duration of the lesion. The distinguishing radiologic features between adults/children and sex were also evaluated. RESULTS : A statistically significant correlation existed between loss of border demarcation and advanced mean age. Multilocular lesions were markedly more common in adults compared to children. Multilocular ABs were associated with increased lesion duration and advanced mean age. Radiologic signs of reactive bony changes associated with the tumour presented at the highest mean duration of all bony effects. Bony expansion and cortical destruction were statistically correlated with lesion duration. Tooth impaction was more common in children. Some mandibular lesions reached a significant size, resulting in impingement of the maxillary sinus, zygoma, orbit and pterygoid plates. CONCLUSION : Due to unfortunate healthcare access constraints, ABs grow to significant sizes and exhibit features not often reported in the literature. The findings of this analysis highlighted the radiologic features of ABs expressed through the mean age and duration of the lesion. This emphasises the significance of timely management of these lesions. en_US
dc.description.department Anatomy en_US
dc.description.department Oral Pathology and Oral Biology en_US
dc.description.librarian hj2024 en_US
dc.description.sdg SDG-03:Good heatlh and well-being en_US
dc.description.uri http://wileyonlinelibrary.com/journal/jop en_US
dc.identifier.citation Smit, C., Robinson L., Ker-Fox, J., Fonseca, F.P., Van Heerden, W.F.P. & Uys, A. Clinicoradiologic features of ameloblastomas: A single-centre study of 155 cases. Journal of Oral Pathology and Medicine 2024; 53 (2): 133‐141. doi: 10.1111/jop.13510. en_US
dc.identifier.issn 0904-2512 (print)
dc.identifier.issn 1600-0714 (online)
dc.identifier.other 10.1111/jop.13510
dc.identifier.uri http://hdl.handle.net/2263/97478
dc.language.iso en en_US
dc.publisher Wiley en_US
dc.rights © 2024 The Authors. Journal of Oral Pathology & Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License. en_US
dc.subject Ameloblastoma en_US
dc.subject Benign odontogenic neoplasm en_US
dc.subject Maxillofacial pathology en_US
dc.subject Maxillofacial radiology en_US
dc.subject SDG-03: Good health and well-being en_US
dc.title Clinicoradiologic features of ameloblastomas : a single-centre study of 155 cases en_US
dc.type Article en_US


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