dc.contributor.author |
Ogola, Edwin
|
|
dc.contributor.author |
Kopp, Anne
|
|
dc.contributor.author |
Bastos, Armanda
|
|
dc.contributor.author |
Slothouwer, Inga
|
|
dc.contributor.author |
Omoga, Dorcus C.A.
|
|
dc.contributor.author |
Osalla, Josephine
|
|
dc.contributor.author |
Sang, Rosemary
|
|
dc.contributor.author |
Torto, Baldwyn
|
|
dc.contributor.author |
Junglen, Sandra
|
|
dc.contributor.author |
Tchouassi, David P.
|
|
dc.date.accessioned |
2024-01-15T12:48:06Z |
|
dc.date.available |
2024-01-15T12:48:06Z |
|
dc.date.issued |
2023-01 |
|
dc.description |
DATA AVAILABILITY : Data will be made available on request. |
en_US |
dc.description.abstract |
Phleboviruses are emerging pathogens of public health importance. However, their association with ticks is
poorly described, particularly in Africa. Here, adult ticks infesting cattle, goats and sheep were collected in two
dryland pastoralist ecosystems of Kenya (Baringo and Kajiado counties) and were screened for infection with
phleboviruses. Ticks mainly belonged to the species Rhipicephalus appendiculatus, Hyalomma impeltatum, and
Hyalomma rufipes. A fragment of the RNA-dependent RNA polymerase (RdRp) gene was identified in thirty of 671
tick pools, of which twenty-nine were from livestock sampled in Baringo county. Phylogenetic analyses revealed
that twenty-five sequences were falling in three clades within the group of tick-associated phleboviruses. The
sequences of the three clades showed nucleotide distances 8%, 19% and 22%, respectively, to previously known
viruses suggesting that these sequence fragments may belong to three distinct viruses. Viruses of the group of
tick-associated phleboviruses have been found in several countries and continents but so far have not been
associated with disease in humans or animals. In addition, five sequences were found to group with the sandflyassociated
phleboviruses Bogoria virus, Perkerra virus and Ntepes virus recently detected in the same region.
Further studies are needed to investigate the transmission and maintenance cycles of these viruses, as well as to
assess their potential to infect vertebrates. |
en_US |
dc.description.department |
Zoology and Entomology |
en_US |
dc.description.librarian |
am2024 |
en_US |
dc.description.sdg |
SDG-03:Good heatlh and well-being |
en_US |
dc.description.sponsorship |
The Deutsche Forschungsgemeinschaft, the German Center for Infection Research (DZIF), Germany, a German Academic Exchange Service (DAAD) through the icipe ARPPIS-DAAD scholarship and a UP postgraduate bursary, a Wellcome Trust International Intermediate Fellowship, the Norad-funded project Combatting Arthropod Pests for better Health, Food and Climate Resilience, Swedish International Development Cooperation Agency (Sida), Swiss Agency for Development and Cooperation (SDC), Australian Centre for International Agricultural Research (ACIAR), Federal Democratic Republic of Ethiopia and the Government of the Republic of Kenya. |
en_US |
dc.description.uri |
https://www.elsevier.com/locate/ttbdis |
en_US |
dc.identifier.citation |
Ogola, E.O., Kopp, A., Bastos, A.D.S. et al. 2023, 'Phlebovirus diversity in ticks from livestock in arid ecologies in Kenya', Ticks and Tick-borne Diseases, vol. 14, art. 102087, pp. 1-9. https://DOI.org/10.1016/j.ttbdis.2022.102087. |
en_US |
dc.identifier.issn |
1877-959X |
|
dc.identifier.other |
10.1016/j.ttbdis.2022.102087 |
|
dc.identifier.uri |
http://hdl.handle.net/2263/93961 |
|
dc.language.iso |
en |
en_US |
dc.publisher |
Elsevier |
en_US |
dc.rights |
© 2022 The Authors.
This is an open access article under the CC BY license. |
en_US |
dc.subject |
Arbovirus |
en_US |
dc.subject |
Phleboviruses |
en_US |
dc.subject |
Tick |
en_US |
dc.subject |
Livestock |
en_US |
dc.subject |
Dryland ecosystem |
en_US |
dc.subject |
Kenya |
en_US |
dc.subject |
SDG-03: Good health and well-being |
en_US |
dc.title |
Phlebovirus diversity in ticks from livestock in arid ecologies in Kenya |
en_US |
dc.type |
Article |
en_US |