COVID-19 vaccines : adverse events following immunisation

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Authors

Van den Berg, Sylvia
Van Rooyen, Cathy
Wessels, Pieter Frederik
Brauer, Marieke
Green, Robin J.

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Allergy Society of South Africa

Abstract

Patients rely on healthcare providers as their most credible and frequent source of vaccine information. It is therefore crucial that healthcare providers are informed and have evidence-based, objective and clear guidance on vaccine efficacy and specific adverse events following immunisation (AEFI). Reported serious AEFIs are extremely rare for the COVID-19 vaccines. This article discusses the main AEFIs attributed to COVID-19 vaccines, including neurological complications of Guillain-Barré syndrome (GBS) and acute transverse myelitis (ATM), thrombosis; cardiac complications, including myocarditis, pericarditis and cardiomyopathy; and allergic reactions such as anaphylaxis, urticaria and skin rashes. The benefits of COVID-19 vaccination outweigh the risks; however, it is important that healthcare providers are aware of the risks and know how to recognise and manage them.

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Keywords

COVID-19 vaccine, Adverse events, Guillain-Barré syndrome (GBS), Acute transverse myelitis (ATM), Thrombosis, Cardiac complications, Myocarditis, Pericarditis, Cardiomyopathy, Vaccine allergy, Urticarial, Skin rash, COVID-19 pandemic, Coronavirus disease 2019 (COVID-19)

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Citation

Van den Berga, S., Van Rooyen, C., Wessels, P.F. et al. 2022, 'COVID-19 vaccines : adverse events following immunisation', Current Allergy and Clinical Immunology, vol. 35, no. 1, pp. 16-22, doi : 10.520/ejc-caci-v35-n1-a3.