High asymptomatic carriage with the Omicron variant in South Africa

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Authors

Garrett, N.
Tapley, Asa
Andriesen, Jessica
Seocharan, Ishen
Fisher, Leigh H.
Bunts, Lisa
Epsy, Nicole
Wallis, Carole L.
Randhawa, April Kaur
Miner, Maurine D.

Journal Title

Journal ISSN

Volume Title

Publisher

Oxford University Press

Abstract

We report a 23% asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) Omicron carriage rate in participants being enrolled into a clinical trial in South Africa, 15-fold higher than in trials before Omicron. We also found lower CD4 + T-cell counts in persons with human immunodeficiency virus (HIV) strongly correlated with increased odds of being SARS-CoV-2 polymerase chain reaction (PCR) positive.

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Keywords

Omicron variant, Asymptomatic carriage, PWH, South Africa (SA), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Human immunodeficiency virus (HIV), Polymerase chain reaction (PCR)

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Citation

Garreett, N., Tapley, A., Andriesen, J. et al. 2022, 'High asymptomatic carriage with the Omicron variant in South Africa', Clinical Infectious Diseases, vol. 75, no. 1, pp. e289-e292, doi : 10.1093/cid/ciac237.