High asymptomatic carriage with the Omicron variant in South Africa

Garrett, N.; Tapley, Asa; Andriesen, Jessica; Seocharan, Ishen; Fisher, Leigh H.; Bunts, Lisa; Epsy, Nicole; Wallis, Carole L.; Randhawa, April Kaur; Miner, Maurine D.; Ketter, Nzeera; Yacovone, Margaret; Goga, Ameena Ebrahim; Huang, Yunda; Hural, John; Kotze, Philip; Bekker, Linda‑Gail; Gray, Glenda E.; Corey, Lawrence; Ubuntu Study Team

dc.contributor.author	Garrett, N.
dc.contributor.author	Tapley, Asa
dc.contributor.author	Andriesen, Jessica
dc.contributor.author	Seocharan, Ishen
dc.contributor.author	Fisher, Leigh H.
dc.contributor.author	Bunts, Lisa
dc.contributor.author	Epsy, Nicole
dc.contributor.author	Wallis, Carole L.
dc.contributor.author	Randhawa, April Kaur
dc.contributor.author	Miner, Maurine D.
dc.contributor.author	Ketter, Nzeera
dc.contributor.author	Yacovone, Margaret
dc.contributor.author	Goga, Ameena Ebrahim
dc.contributor.author	Huang, Yunda
dc.contributor.author	Hural, John
dc.contributor.author	Kotze, Philip
dc.contributor.author	Bekker, Linda‑Gail
dc.contributor.author	Gray, Glenda E.
dc.contributor.author	Corey, Lawrence
dc.contributor.author	Ubuntu Study Team
dc.date.accessioned	2023-05-12T12:15:51Z
dc.date.available	2023-05-12T12:15:51Z
dc.date.issued	2022-07
dc.description.abstract	We report a 23% asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) Omicron carriage rate in participants being enrolled into a clinical trial in South Africa, 15-fold higher than in trials before Omicron. We also found lower CD4 + T-cell counts in persons with human immunodeficiency virus (HIV) strongly correlated with increased odds of being SARS-CoV-2 polymerase chain reaction (PCR) positive.	en_US
dc.description.department	Paediatrics and Child Health	en_US
dc.description.librarian	am2023	en_US
dc.description.sponsorship	The National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) grants. The Sisonke study was funded by the National Treasury of South Africa; the National Department of Health; Solidarity Response Fund NPC; The Michael & Susan Dell Foundation; The Elma Vaccines and Immunization Foundation; and the Bill & Melinda Gates Foundation.	en_US
dc.description.uri	https://academic.oup.com/cid	en_US
dc.identifier.citation	Garreett, N., Tapley, A., Andriesen, J. et al. 2022, 'High asymptomatic carriage with the Omicron variant in South Africa', Clinical Infectious Diseases, vol. 75, no. 1, pp. e289-e292, doi : 10.1093/cid/ciac237.	en_US
dc.identifier.issn	1058-4838 (print)
dc.identifier.issn	1537-6591 (online)
dc.identifier.other	10.1093/cid/ciac237
dc.identifier.uri	http://hdl.handle.net/2263/90659
dc.language.iso	en	en_US
dc.publisher	Oxford University Press	en_US
dc.rights	© The Author(s) 2022. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.	en_US
dc.subject	Omicron variant	en_US
dc.subject	Asymptomatic carriage	en_US
dc.subject	PWH	en_US
dc.subject	South Africa (SA)	en_US
dc.subject	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)	en_US
dc.subject	Human immunodeficiency virus (HIV)	en_US
dc.subject	Polymerase chain reaction (PCR)	en_US
dc.title	High asymptomatic carriage with the Omicron variant in South Africa	en_US
dc.type	Article	en_US