Abstract:
Severe acute respiratory syndrome coronavirus (SARS-CoV-2),
currently the cause of coronavirus disease of 2019 (COVID-19),
has been declared a pandemic. Currently, not many antiviral
treatments are available to effectively treat COVID-19 and therefore
ongoing waves of increasing infection numbers and deaths have
been reported globally. The current repurposing of drugs has been
investigated as possible treatment by researchers and includes
remdesivir and ivermectin. Many natural products have been selected
and investigated for their potential inhibitory activity against SARSCoV-
2, especially those that have previously been identified to
have inhibitory activity against SARS-CoV. There are several genetic
similarities between SARS-CoV-2 and SARS-CoV, such as their
similarities in the genome, the main protease crystal structure and
the primary host receptor (Kaur et al., 2021).
