Lagos bat virus, an under-reported rabies-related lyssavirus

Coertse, Jessica; Geldenhuys, Marike; Le Roux, Kevin; Markotter, Wanda

dc.contributor.author	Coertse, Jessica
dc.contributor.author	Geldenhuys, Marike
dc.contributor.author	Le Roux, Kevin
dc.contributor.author	Markotter, Wanda
dc.date.accessioned	2022-09-08T13:11:42Z
dc.date.available	2022-09-08T13:11:42Z
dc.date.issued	2021-03-29
dc.description.abstract	Lagos bat virus (LBV), one of the 17 accepted viral species of the Lyssavirus genus, was the first rabies-related virus described in 1956. This virus is endemic to the African continent and is rarely encountered. There are currently four lineages, although the observed genetic diversity exceeds existing lyssavirus species demarcation criteria. Several exposures to rabid bats infected with LBV have been reported; however, no known human cases have been reported to date. This review provides the history of LBV and summarizes previous knowledge as well as new detections. Genetic diversity, pathogenesis and prevention are re-evaluated and discussed.	en_US
dc.description.department	Medical Virology	en_US
dc.description.librarian	dm2022	en_US
dc.description.sponsorship	This research is supported in part by the South African Research Chair Initiative (held by Wanda Markotter) of the Department of Science and Innovation and administered by the National Research Foundation of South Africa (UID: 98339). The National Research Foundation funded the equipment based at the DNA Sanger sequencing facility in the Faculty of Natural and Agricultural Sciences, University of Pretoria (UID: 78566).	en_US
dc.description.uri	https://www.mdpi.com/journal/viruses	en_US
dc.identifier.citation	Coertse, J.; Geldenhuys, M.; le Roux, K.; Markotter, W. Lagos Bat Virus, an Under-Reported Rabies-Related Lyssavirus. Viruses 2021, 13, 576. https://doi.org/10.3390/v13040576.	en_US
dc.identifier.issn	1999-4915 (online)
dc.identifier.other	10.3390/v13040576
dc.identifier.uri	https://repository.up.ac.za/handle/2263/87127
dc.language.iso	en	en_US
dc.publisher	MDPI	en_US
dc.rights	© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).	en_US
dc.subject	Lyssavirus	en_US
dc.subject	Bats	en_US
dc.subject	Rabies	en_US
dc.subject	Africa	en_US
dc.subject	Lagos bat lyssavirus (LBV)	en_US
dc.subject	South Africa (SA)	en_US
dc.title	Lagos bat virus, an under-reported rabies-related lyssavirus	en_US
dc.type	Article	en_US