Management of children admitted to hospitals across Bangladesh with suspected or confirmed COVID-19 and the implications for the future : a nationwide cross-sectional study

Show simple item record Chowdhury, Kona Haque, Mainul Nusrat, Nadia Adnan, Nihad Islam, Salequl Lutfor, Afzalunnessa Binte Begum, Dilara Rabbany, Arif Karim, Enamul Malek, Abdul Jahan, Nasim Akter, Jesmine Ashraf, Sumala Hasan, Mohammad Nazmul Hassan, Mahmuda Akhter, Najnin Mazumder, Monika Sihan, Nazmus Naher, Nurun Akter, Shaheen Zaman, Sifat Uz Chowdhury, Tanjina Nesa, Jebun Biswas, Susmita Islam, Mohammod Didarul Hossain, Al Mamun Rahman, Habibur Biswas, Palash Kumar Shaheen, Mohammed Chowdhury, Farah Kumar, Santosh Kurdi, Amanj Mustafa, Zia Ul Schellack, Natalie Gowere, Marshall Meyer, Johanna C. Opanga, Sylvia Godman, Brian 2022-07-15T06:32:22Z 2022-07-15T06:32:22Z 2022-01
dc.description Supplementary Material : File S1: Bangladesh: COVID-19 Pediatric Case Management. en_US
dc.description.abstract There is an increasing focus on researching children admitted to hospital with new variants of COVID-19, combined with concerns with hyperinflammatory syndromes and the overuse of antimicrobials. Paediatric guidelines have been produced in Bangladesh to improve their care. Consequently, the objective is to document the management of children with COVID-19 among 24 hospitals in Bangladesh. Key outcome measures included the percentage prescribed different antimicrobials, adherence to paediatric guidelines and mortality rates using purposely developed report forms. The majority of 146 admitted children were aged 5 years or under (62.3%) and were boys (58.9%). Reasons for admission included fever, respiratory distress and coughing; 86.3% were prescribed antibiotics, typically parenterally, on the WHO ‘Watch’ list, and empirically (98.4%). There were no differences in antibiotic use whether hospitals followed paediatric guidance or not. There was no prescribing of antimalarials and limited prescribing of antivirals (5.5% of children) and antiparasitic medicines (0.7%). The majority of children (92.5%) made a full recovery. It was encouraging to see the low hospitalisation rates and limited use of antimalarials, antivirals and antiparasitic medicines. However, the high empiric use of antibiotics, alongside limited switching to oral formulations, is a concern that can be addressed by instigating the appropriate programmes. en_US
dc.description.department Pharmacology en_US
dc.description.uri en_US
dc.identifier.citation Chowdhury, K.; Haque, M.; Nusrat, N.; Adnan, N.; Islam, S.; Lutfor, A.B.; Begum, D.; Rabbany, A.; Karim, E.; Malek, A.; et al. Management of Children Admitted to Hospitals across Bangladesh with Suspected or Confirmed COVID-19 and the Implications for the Future: A Nationwide Cross-Sectional Study. Antibiotics 2022, 11, 105. en_US
dc.identifier.issn 2079-6382 (online)
dc.identifier.other 10.3390/antibiotics11010105
dc.language.iso en en_US
dc.publisher MDPI en_US
dc.rights © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license. en_US
dc.subject Antibiotics en_US
dc.subject Antimicrobial stewardship programs en_US
dc.subject Bangladesh en_US
dc.subject Children en_US
dc.subject Guidelines en_US
dc.subject Hospitals en_US
dc.subject Outcomes en_US
dc.subject COVID-19 pandemic en_US
dc.subject Coronavirus disease 2019 (COVID-19) en_US
dc.title Management of children admitted to hospitals across Bangladesh with suspected or confirmed COVID-19 and the implications for the future : a nationwide cross-sectional study en_US
dc.type Article en_US

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