Management of children admitted to hospitals across Bangladesh with suspected or confirmed COVID-19 and the implications for the future : a nationwide cross-sectional study

dc.contributor.authorChowdhury, Kona
dc.contributor.authorHaque, Mainul
dc.contributor.authorNusrat, Nadia
dc.contributor.authorAdnan, Nihad
dc.contributor.authorIslam, Salequl
dc.contributor.authorLutfor, Afzalunnessa Binte
dc.contributor.authorBegum, Dilara
dc.contributor.authorRabbany, Arif
dc.contributor.authorKarim, Enamul
dc.contributor.authorMalek, Abdul
dc.contributor.authorJahan, Nasim
dc.contributor.authorAkter, Jesmine
dc.contributor.authorAshraf, Sumala
dc.contributor.authorHasan, Mohammad Nazmul
dc.contributor.authorHassan, Mahmuda
dc.contributor.authorAkhter, Najnin
dc.contributor.authorMazumder, Monika
dc.contributor.authorSihan, Nazmus
dc.contributor.authorNaher, Nurun
dc.contributor.authorAkter, Shaheen
dc.contributor.authorZaman, Sifat Uz
dc.contributor.authorChowdhury, Tanjina
dc.contributor.authorNesa, Jebun
dc.contributor.authorBiswas, Susmita
dc.contributor.authorIslam, Mohammod Didarul
dc.contributor.authorHossain, Al Mamun
dc.contributor.authorRahman, Habibur
dc.contributor.authorBiswas, Palash Kumar
dc.contributor.authorShaheen, Mohammed
dc.contributor.authorChowdhury, Farah
dc.contributor.authorKumar, Santosh
dc.contributor.authorKurdi, Amanj
dc.contributor.authorMustafa, Zia Ul
dc.contributor.authorSchellack, Natalie
dc.contributor.authorGowere, Marshall
dc.contributor.authorMeyer, Johanna C.
dc.contributor.authorOpanga, Sylvia
dc.contributor.authorGodman, Brian
dc.date.accessioned2022-07-15T06:32:22Z
dc.date.available2022-07-15T06:32:22Z
dc.date.issued2022-01
dc.descriptionSupplementary Material : File S1: Bangladesh: COVID-19 Pediatric Case Management.en_US
dc.description.abstractThere is an increasing focus on researching children admitted to hospital with new variants of COVID-19, combined with concerns with hyperinflammatory syndromes and the overuse of antimicrobials. Paediatric guidelines have been produced in Bangladesh to improve their care. Consequently, the objective is to document the management of children with COVID-19 among 24 hospitals in Bangladesh. Key outcome measures included the percentage prescribed different antimicrobials, adherence to paediatric guidelines and mortality rates using purposely developed report forms. The majority of 146 admitted children were aged 5 years or under (62.3%) and were boys (58.9%). Reasons for admission included fever, respiratory distress and coughing; 86.3% were prescribed antibiotics, typically parenterally, on the WHO ‘Watch’ list, and empirically (98.4%). There were no differences in antibiotic use whether hospitals followed paediatric guidance or not. There was no prescribing of antimalarials and limited prescribing of antivirals (5.5% of children) and antiparasitic medicines (0.7%). The majority of children (92.5%) made a full recovery. It was encouraging to see the low hospitalisation rates and limited use of antimalarials, antivirals and antiparasitic medicines. However, the high empiric use of antibiotics, alongside limited switching to oral formulations, is a concern that can be addressed by instigating the appropriate programmes.en_US
dc.description.departmentPharmacologyen_US
dc.description.urihttp://www.mdpi.com/journal/antibioticsen_US
dc.identifier.citationChowdhury, K.; Haque, M.; Nusrat, N.; Adnan, N.; Islam, S.; Lutfor, A.B.; Begum, D.; Rabbany, A.; Karim, E.; Malek, A.; et al. Management of Children Admitted to Hospitals across Bangladesh with Suspected or Confirmed COVID-19 and the Implications for the Future: A Nationwide Cross-Sectional Study. Antibiotics 2022, 11, 105. https://doi.org/10.3390/antibiotics11010105.en_US
dc.identifier.issn2079-6382 (online)
dc.identifier.other10.3390/antibiotics11010105
dc.identifier.urihttps://repository.up.ac.za/handle/2263/86214
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.rights© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.en_US
dc.subjectAntibioticsen_US
dc.subjectAntimicrobial stewardship program (ASP)en_US
dc.subjectBangladeshen_US
dc.subjectChildrenen_US
dc.subjectGuidelinesen_US
dc.subjectHospitalsen_US
dc.subjectOutcomesen_US
dc.subjectCOVID-19 pandemicen_US
dc.subjectCoronavirus disease 2019 (COVID-19)en_US
dc.titleManagement of children admitted to hospitals across Bangladesh with suspected or confirmed COVID-19 and the implications for the future : a nationwide cross-sectional studyen_US
dc.typeArticleen_US

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