Successful treatment of cutaneous squamous cell carcinoma in a captive green iguana (Iguana iguana)

Show simple item record Van der Weyden, Louise O'Dell, Nicolize Avenant, Alida Pazzi, Paolo Koeppel, Katja Natalie 2022-01-21T12:19:53Z 2022-01-21T12:19:53Z 2022-01
dc.description.abstract Reptiles are popular exotic pets and green iguanas (Iguana iguana) are amongst the top ten most popular reptiles. Here we describe a captive 8-year-old female green iguana that was referred for treatment of a non-healing, discharging lesion on the side of the body. The lesion was surgically excised and histopathological analysis revealed an epidermal proliferation of neoplastic keratinocytes, with focal infiltration through the basement membrane, into the underlying superficial dermis. Marked dysplastic changes, characterized by multifocal dyskeratosis and keratin pearl formation were also noted. A diagnosis of cutaneous squamous cell carcinoma (SCC) was made. Two years later, the iguana has shown no signs of recurrence. This is the first report of successful treatment of cutaneous SCC in a green iguana and contributes to the limited knowledge of cutaneous neoplasms in green iguanas. en_ZA
dc.description.department Centre for Veterinary Wildlife Studies en_ZA
dc.description.department Companion Animal Clinical Studies en_ZA
dc.description.department Paraclinical Sciences en_ZA
dc.description.department Production Animal Studies en_ZA
dc.description.librarian hj2022 en_ZA
dc.description.sponsorship The Wellcome Trust en_ZA
dc.description.uri en_ZA
dc.identifier.citation Van der Weyden L., O'Dell N., Avenant A. et al. 2022, 'Successful treatment of cutaneous squamous cell carcinoma in a captive green iguana (Iguana iguana)', Topics in Companion Animal Medicine, vol. 46, art. 100610, pp. 1-4. en_ZA
dc.identifier.issn 1938-9736
dc.identifier.other 10.1016/j.tcam.2021.100610
dc.language.iso en en_ZA
dc.publisher Elsevier en_ZA
dc.rights © 2021 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license ( en_ZA
dc.subject Lizard en_ZA
dc.subject Cancer en_ZA
dc.subject Green iguanas (Iguana iguana) en_ZA
dc.subject Squamous cell carcinoma (SCC) en_ZA
dc.subject Dyskeratosis en_ZA
dc.subject Keratin pearl en_ZA
dc.subject Skin en_ZA
dc.subject Treatment en_ZA
dc.subject Surgery en_ZA
dc.subject.other Veterinary science articles SDG-15 en_ZA
dc.subject.other SDG-15: Life on land
dc.title Successful treatment of cutaneous squamous cell carcinoma in a captive green iguana (Iguana iguana) en_ZA
dc.type Article en_ZA

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