Successful treatment of cutaneous squamous cell carcinoma in a captive green iguana (Iguana iguana)

dc.contributor.authorVan der Weyden, Louise
dc.contributor.authorO'Dell, Nicolize
dc.contributor.authorAvenant, Alida
dc.contributor.authorPazzi, Paolo
dc.contributor.authorKoeppel, Katja Natalie
dc.contributor.emailkatja.koeppel@up.ac.zaen_ZA
dc.date.accessioned2022-01-21T12:19:53Z
dc.date.available2022-01-21T12:19:53Z
dc.date.issued2022-01
dc.description.abstractReptiles are popular exotic pets and green iguanas (Iguana iguana) are amongst the top ten most popular reptiles. Here we describe a captive 8-year-old female green iguana that was referred for treatment of a non-healing, discharging lesion on the side of the body. The lesion was surgically excised and histopathological analysis revealed an epidermal proliferation of neoplastic keratinocytes, with focal infiltration through the basement membrane, into the underlying superficial dermis. Marked dysplastic changes, characterized by multifocal dyskeratosis and keratin pearl formation were also noted. A diagnosis of cutaneous squamous cell carcinoma (SCC) was made. Two years later, the iguana has shown no signs of recurrence. This is the first report of successful treatment of cutaneous SCC in a green iguana and contributes to the limited knowledge of cutaneous neoplasms in green iguanas.en_ZA
dc.description.departmentCentre for Veterinary Wildlife Studiesen_ZA
dc.description.departmentCompanion Animal Clinical Studiesen_ZA
dc.description.departmentParaclinical Sciencesen_ZA
dc.description.departmentProduction Animal Studiesen_ZA
dc.description.librarianhj2022en_ZA
dc.description.sponsorshipThe Wellcome Trusten_ZA
dc.description.urihttps://www.sciencedirect.com/journal/topics-in-companion-animal-medicineen_ZA
dc.identifier.citationVan der Weyden L., O'Dell N., Avenant A. et al. 2022, 'Successful treatment of cutaneous squamous cell carcinoma in a captive green iguana (Iguana iguana)', Topics in Companion Animal Medicine, vol. 46, art. 100610, pp. 1-4.en_ZA
dc.identifier.issn1938-9736
dc.identifier.other10.1016/j.tcam.2021.100610
dc.identifier.urihttp://hdl.handle.net/2263/83418
dc.language.isoenen_ZA
dc.publisherElsevieren_ZA
dc.rights© 2021 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).en_ZA
dc.subjectLizarden_ZA
dc.subjectCanceren_ZA
dc.subjectGreen iguanas (Iguana iguana)en_ZA
dc.subjectSquamous cell carcinoma (SCC)en_ZA
dc.subjectDyskeratosisen_ZA
dc.subjectKeratin pearlen_ZA
dc.subjectSkinen_ZA
dc.subjectTreatmenten_ZA
dc.subjectSurgeryen_ZA
dc.subject.otherVeterinary science articles SDG-15en_ZA
dc.subject.otherSDG-15: Life on land
dc.titleSuccessful treatment of cutaneous squamous cell carcinoma in a captive green iguana (Iguana iguana)en_ZA
dc.typeArticleen_ZA

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