Structure−activity relationship studies reveal new astemizole analogues active against Plasmodium falciparum in vitro

Mambwe, Dickson; Kumar, Malkeet; Ferger, Richard; Taylor, Dale; Njoroge, Mathew; Coertzen, Dina; Reader, Janette; Van der Watt, Mariette Elizabeth; Birkholtz, Lyn-Marie; Chibale, Kelly

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dc.contributor.author	Mambwe, Dickson
dc.contributor.author	Kumar, Malkeet
dc.contributor.author	Ferger, Richard
dc.contributor.author	Taylor, Dale
dc.contributor.author	Njoroge, Mathew
dc.contributor.author	Coertzen, Dina
dc.contributor.author	Reader, Janette
dc.contributor.author	Van der Watt, Mariette Elizabeth
dc.contributor.author	Birkholtz, Lyn-Marie
dc.contributor.author	Chibale, Kelly
dc.date.accessioned	2021-10-15T11:57:00Z
dc.date.issued	2021-08
dc.description.abstract	Please read abstract in the article.	en_ZA
dc.description.department	Biochemistry	en_ZA
dc.description.department	Genetics	en_ZA
dc.description.department	Microbiology and Plant Pathology	en_ZA
dc.description.embargo	2022-08-02
dc.description.librarian	hj2021	en_ZA
dc.description.uri	https://pubs.acs.org/journal/aidcbc	en_ZA
dc.identifier.citation	Mambwe, D., Kumar, M., Ferger, R. et al. 2021, 'Structure−activity relationship studies reveal new astemizole analogues active against Plasmodium falciparum in vitro', ACS Medicinal Chemistry Letters, vol. 12, no. 8, pp. 1333-1341.	en_ZA
dc.identifier.issn	1948-5875
dc.identifier.other	10.1021/acsmedchemlett.1c00328
dc.identifier.uri	http://hdl.handle.net/2263/82130
dc.language.iso	en	en_ZA
dc.publisher	American Chemical Society	en_ZA
dc.rights	© 2021 American Chemical Society	en_ZA
dc.subject	Astemizole	en_ZA
dc.subject	Plasmodium falciparum	en_ZA
dc.subject	Repositioning	en_ZA
dc.subject	Human ether-a-go-go-related gene	en_ZA
dc.title	Structure−activity relationship studies reveal new astemizole analogues active against Plasmodium falciparum in vitro	en_ZA
dc.type	Postprint Article	en_ZA