dc.contributor.author |
Honiball, John Robert
|
|
dc.contributor.author |
Pepper, Michael Sean
|
|
dc.contributor.author |
Prinsloo, Earl
|
|
dc.date.accessioned |
2021-06-29T05:09:01Z |
|
dc.date.available |
2021-06-29T05:09:01Z |
|
dc.date.issued |
2021 |
|
dc.description.abstract |
Bioprinting is a rapidly expanding technology with the ability to fabricate in vitro three-dimensional (3D) tissues in a layer-by-layer manner to ultimately produce a living tissue which physiologically resembles native in vivo tissue functionality. Unfortunately, large costs associated with commercially available bioprinters severely limit access to the technology. We investigated the potential for modifying a low-cost commercially available RepRap Prusa iteration 3 (i3) 3D printer with an open-source syringe-housed microextrusion print-head unit (universal paste extruder by Richard Horne, RichRap), that allowed for controlled deposition of cell-laden bioinks and Freeform Reversible Embedding of Suspended Hydrogels (FRESH) method-based printing. |
en_ZA |
dc.description.department |
Immunology |
en_ZA |
dc.description.librarian |
hj2021 |
en_ZA |
dc.description.sponsorship |
The National Research Foundation of South Africa, the South African Medical Research Council (SAMRC) and Rhodes University for funding. JRH was the recipient of an Ada & Bertie Levenstein Bursary. |
en_ZA |
dc.description.uri |
http://www.elsevier.com/locate/mex |
en_ZA |
dc.identifier.citation |
Honiball, J.R., Pepper, M.S. & Prinsloo, E. 2021, 'Step-by-step assembly and testing of a low-cost bioprinting solution for research and educational purposes', MethodsX, vol. 8, 2021, art. 101186, pp. 1-9. |
en_ZA |
dc.identifier.issn |
2215-0161 (online) |
|
dc.identifier.other |
10.1016/j.mex.2020.101186 |
|
dc.identifier.uri |
http://hdl.handle.net/2263/80634 |
|
dc.language.iso |
en |
en_ZA |
dc.publisher |
Elsevier |
en_ZA |
dc.rights |
© 2020 Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license. |
en_ZA |
dc.subject |
Bioprinting |
en_ZA |
dc.subject |
Sodium alginate |
en_ZA |
dc.subject |
Freeform reversible embedding of suspended hydrogels (FRESH) |
en_ZA |
dc.subject |
Additive manufacturing (AM) |
en_ZA |
dc.title |
Step-by-step assembly and testing of a low-cost bioprinting solution for research and educational purposes |
en_ZA |
dc.type |
Article |
en_ZA |