Step-by-step assembly and testing of a low-cost bioprinting solution for research and educational purposes

dc.contributor.authorHoniball, John Robert
dc.contributor.authorPepper, Michael Sean
dc.contributor.authorPrinsloo, Earl
dc.date.accessioned2021-06-29T05:09:01Z
dc.date.available2021-06-29T05:09:01Z
dc.date.issued2021
dc.description.abstractBioprinting is a rapidly expanding technology with the ability to fabricate in vitro three-dimensional (3D) tissues in a layer-by-layer manner to ultimately produce a living tissue which physiologically resembles native in vivo tissue functionality. Unfortunately, large costs associated with commercially available bioprinters severely limit access to the technology. We investigated the potential for modifying a low-cost commercially available RepRap Prusa iteration 3 (i3) 3D printer with an open-source syringe-housed microextrusion print-head unit (universal paste extruder by Richard Horne, RichRap), that allowed for controlled deposition of cell-laden bioinks and Freeform Reversible Embedding of Suspended Hydrogels (FRESH) method-based printing.en_ZA
dc.description.departmentImmunologyen_ZA
dc.description.librarianhj2021en_ZA
dc.description.sponsorshipThe National Research Foundation of South Africa, the South African Medical Research Council (SAMRC) and Rhodes University for funding. JRH was the recipient of an Ada & Bertie Levenstein Bursary.en_ZA
dc.description.urihttp://www.elsevier.com/locate/mexen_ZA
dc.identifier.citationHoniball, J.R., Pepper, M.S. & Prinsloo, E. 2021, 'Step-by-step assembly and testing of a low-cost bioprinting solution for research and educational purposes', MethodsX, vol. 8, 2021, art. 101186, pp. 1-9.en_ZA
dc.identifier.issn2215-0161 (online)
dc.identifier.other10.1016/j.mex.2020.101186
dc.identifier.urihttp://hdl.handle.net/2263/80634
dc.language.isoenen_ZA
dc.publisherElsevieren_ZA
dc.rights© 2020 Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license.en_ZA
dc.subjectBioprintingen_ZA
dc.subjectSodium alginateen_ZA
dc.subjectFreeform reversible embedding of suspended hydrogels (FRESH)en_ZA
dc.subjectAdditive manufacturing (AM)en_ZA
dc.titleStep-by-step assembly and testing of a low-cost bioprinting solution for research and educational purposesen_ZA
dc.typeArticleen_ZA

Files

Original bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Honiball_StepByStep_2021.pdf
Size:
1.14 MB
Format:
Adobe Portable Document Format
Description:
Article

License bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
license.txt
Size:
1.75 KB
Format:
Item-specific license agreed upon to submission
Description: