Step-by-step assembly and testing of a low-cost bioprinting solution for research and educational purposes
dc.contributor.author | Honiball, John Robert | |
dc.contributor.author | Pepper, Michael Sean | |
dc.contributor.author | Prinsloo, Earl | |
dc.date.accessioned | 2021-06-29T05:09:01Z | |
dc.date.available | 2021-06-29T05:09:01Z | |
dc.date.issued | 2021 | |
dc.description.abstract | Bioprinting is a rapidly expanding technology with the ability to fabricate in vitro three-dimensional (3D) tissues in a layer-by-layer manner to ultimately produce a living tissue which physiologically resembles native in vivo tissue functionality. Unfortunately, large costs associated with commercially available bioprinters severely limit access to the technology. We investigated the potential for modifying a low-cost commercially available RepRap Prusa iteration 3 (i3) 3D printer with an open-source syringe-housed microextrusion print-head unit (universal paste extruder by Richard Horne, RichRap), that allowed for controlled deposition of cell-laden bioinks and Freeform Reversible Embedding of Suspended Hydrogels (FRESH) method-based printing. | en_ZA |
dc.description.department | Immunology | en_ZA |
dc.description.librarian | hj2021 | en_ZA |
dc.description.sponsorship | The National Research Foundation of South Africa, the South African Medical Research Council (SAMRC) and Rhodes University for funding. JRH was the recipient of an Ada & Bertie Levenstein Bursary. | en_ZA |
dc.description.uri | http://www.elsevier.com/locate/mex | en_ZA |
dc.identifier.citation | Honiball, J.R., Pepper, M.S. & Prinsloo, E. 2021, 'Step-by-step assembly and testing of a low-cost bioprinting solution for research and educational purposes', MethodsX, vol. 8, 2021, art. 101186, pp. 1-9. | en_ZA |
dc.identifier.issn | 2215-0161 (online) | |
dc.identifier.other | 10.1016/j.mex.2020.101186 | |
dc.identifier.uri | http://hdl.handle.net/2263/80634 | |
dc.language.iso | en | en_ZA |
dc.publisher | Elsevier | en_ZA |
dc.rights | © 2020 Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license. | en_ZA |
dc.subject | Bioprinting | en_ZA |
dc.subject | Sodium alginate | en_ZA |
dc.subject | Freeform reversible embedding of suspended hydrogels (FRESH) | en_ZA |
dc.subject | Additive manufacturing (AM) | en_ZA |
dc.title | Step-by-step assembly and testing of a low-cost bioprinting solution for research and educational purposes | en_ZA |
dc.type | Article | en_ZA |