Factors associated with mortality in children under five years old hospitalized for severe acute malnutrition in Limpopo province, South Africa, 2014-2018 : a cross-sectional analytic study

Show simple item record

dc.contributor.author Gavhi, Fhatuwani
dc.contributor.author Kuonza, Lazarus R.
dc.contributor.author Musekiwa, Alfred
dc.contributor.author Motaze, Nkengafac Villyen
dc.date.accessioned 2021-04-19T06:20:43Z
dc.date.available 2021-04-19T06:20:43Z
dc.date.issued 2020-05-08
dc.description S1 File. Ethical approval letter. en_ZA
dc.description S1 Dataset. Manuscript data. en_ZA
dc.description.abstract BACKGROUND : In South Africa, 30.9% of children under five years with Severe Acute Malnutrition (SAM) died in 2018. We aimed to identify factors associated with mortality among children under five years hospitalized with SAM in Limpopo province, South Africa. METHODS : We conducted a cross-sectional study including children under five years admitted with SAM from 2014 to 2018 in public hospitals of Limpopo province. We extracted socio-demographic and clinical data from hospital records. We used logistic regression to identify factors associated with mortality. FINDINGS : We included 956 children, 50.2% (480/956) male and 49.8% (476/956) female. The median age was 13 months (inter quartile range: 9–19 months). The overall SAM mortality over the study period was 25.9% (248/956). The most common complications were diarrhea, 63.8% (610/956), and lower respiratory tract infections (LRTIs), 42.4% (405/956). Factors associated with mortality included herbal medication use (adjusted Odds Ratio (aOR): 2.2, 95% Confidence Interval (CI): 1.4–3.5, p = 0.001), poor appetite (aOR: 2.7, 95% CI: 1.4–5.2, p = 0.003), Mid-upper circumference (MUAC) <11.5 cm (aOR: 3.0, 95% CI: 1.9–4.7, p<0.001), lower respiratory tract infections (LRTIs) (aOR: 1.6, 95% CI: 1.2–2.0, p<0.001), anemia (aOR: 2.5, 95% CI: 1.1–5.3, p = 0.021), hypoglycemia (aOR: 12.4, 95% CI: 7.1–21.8, p<0.001) and human immunodeficiency virus (HIV) infection (aOR: 2.3, 95% CI: 1.6–3.3, p<0.001). INTERPRETATION : Herbal medication use, poor appetite, LRTIs, anemia, hypoglycemia, and HIV infection were associated with mortality among children with SAM. These factors should guide management of children with SAM. en_ZA
dc.description.department School of Health Systems and Public Health (SHSPH) en_ZA
dc.description.librarian am2021 en_ZA
dc.description.uri http://www.plosone.org en_ZA
dc.identifier.citation Gavhi F, Kuonza L, Musekiwa A, Motaze NV (2020) Factors associated with mortality in children under five years old hospitalized for Severe Acute Malnutrition in Limpopo province, South Africa, 2014-2018: A cross-sectional analytic study. PLoS ONE 15(5): e0232838. https://DOI.org/10.1371/journal.pone.0232838. en_ZA
dc.identifier.issn 1932-6203 (online)
dc.identifier.other 10.1371/journal.pone.0232838
dc.identifier.uri http://hdl.handle.net/2263/79485
dc.language.iso en en_ZA
dc.publisher Public Library of Science en_ZA
dc.rights © 2020 Gavhi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License. en_ZA
dc.subject Mortality en_ZA
dc.subject Children en_ZA
dc.subject Limpopo province, South Africa en_ZA
dc.subject Severe acute malnutrition (SAM) en_ZA
dc.title Factors associated with mortality in children under five years old hospitalized for severe acute malnutrition in Limpopo province, South Africa, 2014-2018 : a cross-sectional analytic study en_ZA
dc.type Article en_ZA


Files in this item

This item appears in the following Collection(s)

Show simple item record