Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born thoroughbred foals

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dc.contributor.author Brown, Lara Jean
dc.contributor.author Brown, Geoffrey James
dc.contributor.author Kydd, Julia
dc.contributor.author Stout, T.A.E. (Tom)
dc.contributor.author Schulman, M.L. (Martin)
dc.date.accessioned 2021-01-05T05:14:05Z
dc.date.available 2021-01-05T05:14:05Z
dc.date.issued 2019-05-30
dc.description This article is based on the MSc thesis of L.J.B. entitled ‘Failure to detect equid herpesvirus type 1 DNA in thoroughbred placentae and healthy new-born foals’. (http://hdl.handle.net/2263/67946) en_ZA
dc.description.abstract Equid herpesvirus type 1 is primarily a respiratory tract virus associated with poor athletic performance that can also cause late gestation abortion, neonatal foal death and encephalomyelopathy. Horizontal transmission is well described, whereas evidence of vertical transmission of equid herpesvirus type 1 associated with the birth of a healthy foal has not been demonstrated. This study sampled a population of Thoroughbred mares (n = 71), and their healthy neonatal foals and foetal membranes, to test for the presence of both equid herpesvirus types 1 and 4 using a quantitative polymerase chain reaction assay. Foetal membrane swabs and tissue samples were taken immediately post-partum, and venous blood samples and nasal swabs were obtained from both mare and foal 8 h after birth. Neither equid herpesvirus type 1 nor equid herpesvirus type 4 nucleic acid was detected in any sample, and it was concluded that there was no active shedding of equid herpesvirus types 1 and 4 at the time of sampling. Consequently, no evidence of vertical transmission of these viruses could be found on this stud farm during the sampling period. en_ZA
dc.description.department Production Animal Studies en_ZA
dc.description.librarian am2020 en_ZA
dc.description.sponsorship The Wits Health Consortium and a University of Pretoria Postgraduate Bursary. The article processing charges were partially funded by the South African Veterinary Association. en_ZA
dc.description.uri http://www.jsava.co.za en_ZA
dc.identifier.citation Brown, L.J., Brown, G., Kydd, J., Stout, T.A.E. & Schulman, M.L., 2019, ‘Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born Thoroughbred foals’, Journal of the South African Veterinary Association 90(0), a1736. https://DOI.org/ 10.4102/jsava.v90i0.1736. en_ZA
dc.identifier.issn 1019-9128 (print)
dc.identifier.issn 2224-9435 (online)
dc.identifier.other 10.4102/ jsava.v90i0.1736
dc.identifier.uri http://hdl.handle.net/2263/77917
dc.language.iso en en_ZA
dc.publisher AOSIS OpenJournals en_ZA
dc.rights © 2019. The Authors. Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License. en_ZA
dc.subject Equines en_ZA
dc.subject Placentae en_ZA
dc.subject Foetal membranes en_ZA
dc.subject Foals en_ZA
dc.subject qPCR en_ZA
dc.subject Latency en_ZA
dc.subject Equid herpesvirus type 1 en_ZA
dc.subject Equid herpesvirus type 4 en_ZA
dc.subject Thoroughbred horse en_ZA
dc.title Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born thoroughbred foals en_ZA
dc.type Article en_ZA


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