Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born thoroughbred foals

dc.contributor.authorBrown, Lara Jean
dc.contributor.authorBrown, Geoffrey James
dc.contributor.authorKydd, Julia
dc.contributor.authorStout, T.A.E. (Tom)
dc.contributor.authorSchulman, M.L. (Martin)
dc.date.accessioned2021-01-05T05:14:05Z
dc.date.available2021-01-05T05:14:05Z
dc.date.issued2019-05-30
dc.descriptionThis article is based on the MSc thesis of L.J.B. entitled ‘Failure to detect equid herpesvirus type 1 DNA in thoroughbred placentae and healthy new-born foals’. (http://hdl.handle.net/2263/67946)en_ZA
dc.description.abstractEquid herpesvirus type 1 is primarily a respiratory tract virus associated with poor athletic performance that can also cause late gestation abortion, neonatal foal death and encephalomyelopathy. Horizontal transmission is well described, whereas evidence of vertical transmission of equid herpesvirus type 1 associated with the birth of a healthy foal has not been demonstrated. This study sampled a population of Thoroughbred mares (n = 71), and their healthy neonatal foals and foetal membranes, to test for the presence of both equid herpesvirus types 1 and 4 using a quantitative polymerase chain reaction assay. Foetal membrane swabs and tissue samples were taken immediately post-partum, and venous blood samples and nasal swabs were obtained from both mare and foal 8 h after birth. Neither equid herpesvirus type 1 nor equid herpesvirus type 4 nucleic acid was detected in any sample, and it was concluded that there was no active shedding of equid herpesvirus types 1 and 4 at the time of sampling. Consequently, no evidence of vertical transmission of these viruses could be found on this stud farm during the sampling period.en_ZA
dc.description.departmentProduction Animal Studiesen_ZA
dc.description.librarianam2020en_ZA
dc.description.sponsorshipThe Wits Health Consortium and a University of Pretoria Postgraduate Bursary. The article processing charges were partially funded by the South African Veterinary Association.en_ZA
dc.description.urihttp://www.jsava.co.zaen_ZA
dc.identifier.citationBrown, L.J., Brown, G., Kydd, J., Stout, T.A.E. & Schulman, M.L., 2019, ‘Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born Thoroughbred foals’, Journal of the South African Veterinary Association 90(0), a1736. https://DOI.org/ 10.4102/jsava.v90i0.1736.en_ZA
dc.identifier.issn1019-9128 (print)
dc.identifier.issn2224-9435 (online)
dc.identifier.other10.4102/ jsava.v90i0.1736
dc.identifier.urihttp://hdl.handle.net/2263/77917
dc.language.isoenen_ZA
dc.publisherAOSIS OpenJournalsen_ZA
dc.rights© 2019. The Authors. Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License.en_ZA
dc.subjectEquinesen_ZA
dc.subjectPlacentaeen_ZA
dc.subjectFoetal membranesen_ZA
dc.subjectFoalsen_ZA
dc.subjectqPCRen_ZA
dc.subjectLatencyen_ZA
dc.subjectEquid herpesvirus type 1en_ZA
dc.subjectEquid herpesvirus type 4en_ZA
dc.subjectThoroughbred horseen_ZA
dc.titleFailure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born thoroughbred foalsen_ZA
dc.typeArticleen_ZA

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