Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born thoroughbred foals
dc.contributor.author | Brown, Lara Jean | |
dc.contributor.author | Brown, Geoffrey James | |
dc.contributor.author | Kydd, Julia | |
dc.contributor.author | Stout, T.A.E. (Tom) | |
dc.contributor.author | Schulman, M.L. (Martin) | |
dc.date.accessioned | 2021-01-05T05:14:05Z | |
dc.date.available | 2021-01-05T05:14:05Z | |
dc.date.issued | 2019-05-30 | |
dc.description | This article is based on the MSc thesis of L.J.B. entitled ‘Failure to detect equid herpesvirus type 1 DNA in thoroughbred placentae and healthy new-born foals’. (http://hdl.handle.net/2263/67946) | en_ZA |
dc.description.abstract | Equid herpesvirus type 1 is primarily a respiratory tract virus associated with poor athletic performance that can also cause late gestation abortion, neonatal foal death and encephalomyelopathy. Horizontal transmission is well described, whereas evidence of vertical transmission of equid herpesvirus type 1 associated with the birth of a healthy foal has not been demonstrated. This study sampled a population of Thoroughbred mares (n = 71), and their healthy neonatal foals and foetal membranes, to test for the presence of both equid herpesvirus types 1 and 4 using a quantitative polymerase chain reaction assay. Foetal membrane swabs and tissue samples were taken immediately post-partum, and venous blood samples and nasal swabs were obtained from both mare and foal 8 h after birth. Neither equid herpesvirus type 1 nor equid herpesvirus type 4 nucleic acid was detected in any sample, and it was concluded that there was no active shedding of equid herpesvirus types 1 and 4 at the time of sampling. Consequently, no evidence of vertical transmission of these viruses could be found on this stud farm during the sampling period. | en_ZA |
dc.description.department | Production Animal Studies | en_ZA |
dc.description.librarian | am2020 | en_ZA |
dc.description.sponsorship | The Wits Health Consortium and a University of Pretoria Postgraduate Bursary. The article processing charges were partially funded by the South African Veterinary Association. | en_ZA |
dc.description.uri | http://www.jsava.co.za | en_ZA |
dc.identifier.citation | Brown, L.J., Brown, G., Kydd, J., Stout, T.A.E. & Schulman, M.L., 2019, ‘Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born Thoroughbred foals’, Journal of the South African Veterinary Association 90(0), a1736. https://DOI.org/ 10.4102/jsava.v90i0.1736. | en_ZA |
dc.identifier.issn | 1019-9128 (print) | |
dc.identifier.issn | 2224-9435 (online) | |
dc.identifier.other | 10.4102/ jsava.v90i0.1736 | |
dc.identifier.uri | http://hdl.handle.net/2263/77917 | |
dc.language.iso | en | en_ZA |
dc.publisher | AOSIS OpenJournals | en_ZA |
dc.rights | © 2019. The Authors. Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License. | en_ZA |
dc.subject | Equines | en_ZA |
dc.subject | Placentae | en_ZA |
dc.subject | Foetal membranes | en_ZA |
dc.subject | Foals | en_ZA |
dc.subject | qPCR | en_ZA |
dc.subject | Latency | en_ZA |
dc.subject | Equid herpesvirus type 1 | en_ZA |
dc.subject | Equid herpesvirus type 4 | en_ZA |
dc.subject | Thoroughbred horse | en_ZA |
dc.title | Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born thoroughbred foals | en_ZA |
dc.type | Article | en_ZA |