Imaging bacteria with radiolabelled probes : is it feasible?

Show simple item record Signore, Alberto Artiko, Vera Conserva, Martina Ferro-Flores, Guillermina Welling, Mick M. Jain, Sanjay K. Hess, Soren Sathekge, Mike Machaba 2020-11-04T08:26:51Z 2020-11-04T08:26:51Z 2020-07-25
dc.description Conceptualization of this paper was made by A.S. and M.S.; data were obtained and analyzed by G.F.-F., M.M.W. and S.K.J. and S.H.; draft preparation by M.C. and A.S.; review and editing by A.S., V.A., M.C., G.F.-F., M.M.W., S.K.J., S.H. and M.S. en_ZA
dc.description.abstract Bacterial infections are the main cause of patient morbidity and mortality worldwide. Diagnosis can be di cult and delayed as well as the identification of the etiological pathogen, necessary for a tailored antibiotic therapy. Several non-invasive diagnostic procedures are available, all with pros and cons. Molecular nuclear medicine has highly contributed in this field by proposing several di erent radiopharmaceuticals (antimicrobial peptides, leukocytes, cytokines, antibiotics, sugars, etc.) but none proved to be highly specific for bacteria, although many agents in development look promising. Indeed, factors including the number and strain of bacteria, the infection site, and the host condition, may a ect the specificity of the tested radiopharmaceuticals. At the Third European Congress on Infection/Inflammation Imaging, a round table discussion was dedicated to debate the pros and cons of di erent radiopharmaceuticals for imaging bacteria with the final goal to find a consensus on the most relevant research steps that should be fulfilled when testing a new probe, based on experience and cumulative published evidence. en_ZA
dc.description.department Nuclear Medicine en_ZA
dc.description.librarian am2020 en_ZA
dc.description.uri en_ZA
dc.identifier.citation Signore, A., Artiko, V., Conserva, M. et al. 2020, 'Imaging bacteria with radiolabelled probes : is it feasible?', Journal of Clinical Medicine, vol. 9, art. 2372, pp. 1-10. en_ZA
dc.identifier.issn 2077-0383 (print)
dc.identifier.other 10.3390/jcm9082372
dc.language.iso en en_ZA
dc.publisher MDPI en_ZA
dc.rights © 2020 by the authors. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license. en_ZA
dc.subject Infection en_ZA
dc.subject Bacteria en_ZA
dc.subject Radiopharmaceutical en_ZA
dc.subject Molecular imaging en_ZA
dc.subject Nuclear medicine en_ZA
dc.title Imaging bacteria with radiolabelled probes : is it feasible? en_ZA
dc.type Article en_ZA

Files in this item

This item appears in the following Collection(s)

Show simple item record