How are countries in sub-Saharan African monitoring the impact of programmes to prevent vertical transmission of HIV?

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Authors

Goga, Ameena Ebrahim
Singh, Yagespari
Jackson, Debra
Mukungunugwa, Solomon
Wafula, Rose
Eliya, Michael
Ng’ambi, Wingston Felix
Nabitaka, Linda
Chirinda, Witness
Bhardwaj, Sanjana

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BMJ Publishing Group

Abstract

Vertical transmission of HIV can occur during pregnancy, delivery, or through breast feeding. The main driver of vertical transmission is a high maternal viral load. Between 2002 and 2016, low and middle income countries (LMICs) in sub-Saharan Africa with high HIV prevalence improved their policies to prevent vertical transmission of HIV. In 2002, national policies recommended single dose nevirapine at the onset of labour, with limited or no breast feeding. By 2016, all Global Plan priority countries in sub-Saharan Africa (where 90% of the world’s HIV positive pregnant women live) had adopted Option B+ with promotion of breast feeding. Option B+ was a dramatic policy change recommending lifelong triple antiretroviral therapy (ART) for all pregnant and lactating women living with HIV. The aim is to protect the child from HIV infection, ensure the mother’s future health, and prevent horizontal transmission of HIV.

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Keywords

Transmission, Infection, Pregnancy, Human immunodeficiency virus (HIV), Vertical transmission, Low- and middle-income countries (LMICs), Sub-Saharan Africa (SSA), Antiretroviral therapy (ART)

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Citation

Goga, A., Singh, Y., Jackson, D. et al. How are countries in sub-Saharan African monitoring the impact of programmes to prevent vertical transmission of HIV? BMJ 2019;364:l660 http://dx.DOI.org/10.1136/bmj.l660.