Salmonella is among the pathogens on the high global priority lists for monitoring for studies
on the discovery of new antimicrobials and understanding of how antimicrobial resistance (AMR)
develops. AMR in connection with antibiotic usage patterns has been considered as a strong factor
and contributor to the AMR pool. The purposes of use, pattern of antimicrobial drug administration,
as well as the prevalence of AMR in Salmonella originating from the Nigeria broiler production value
chain (NBPVC) was explored. A well-structured questionnaire on antimicrobial usage (n = 181) was
used for sampling that focused on 21 antimicrobials from 151 locations. Simultaneously, AMR testing
for 18 commonly used antimicrobials on Salmonella in humans was also carried out. Antimicrobial
resistance Salmonella spp. were isolated in 23% of the samples (261 of 1135 samples from the broiler
input, products, and the environment) using modified ISO 6579 and invA PCR protocols. Over 80%
of the antimicrobials used in the NBPVC were administered without a veterinarian prescription.
Prevalence of antimicrobial administration without prescription were as follows: live-bird-market
(100%), hatchery (86.7%), grow-out-farm (75%), and breeder (66.7%). Widespread prophylactic and
metaphylactic use of antimicrobials were recorded with the highest use seen for enrofloxacin (63%
and 24%), tetracycline (58% and 33%), and erythromycin (50% and 17%). Antimicrobial resistance was
highest for flumequine (100%), penicillin (95%), and perfloxacin (89%). High levels of use without
laboratory support of a newer generation of a class of antibiotics suspected to confer high resistance
on older generations of the same class (quinolones) was observed.
Oguttu, James Wabwire(University of Pretoria, 2008-08-07)
The usage of antimicrobials either as performance enhancers or for prophylactic and therapeutic purposes in food animals, such as chickens, increases the prevalence of antimicrobial drug resistance among enteric bacteria ...
Antimicrobial usage in food animals increases the prevalence of antimicrobial drug resistance among their enteric bacteria. It has been suggested that this resistance can in turn be transferred to people working with such ...
Chermprapai, Suttiwee; Ederveen, Thomas H.A.; Broere, Femke; Broens, Els M.; Schlotter, Yvette M.; Van Schalkwijk, Saskia; Boekhorst, Jos; van Hijum, Sacha A.F.T.; Rutten, Victor P.M.G.(Elsevier, 2019-02)
Canine atopic dermatitis is a genetically predisposed inflammatory and pruritic allergic skin disease that is often
complicated by (secondary) bacterial and fungal (yeast) infections. High-throughput DNA sequencing was ...