Attempted molecular detection of the thermally dimorphic human fungal pathogen Emergomyces africanus in terrestrial small mammals in South Africa

Cronje, Nadine; Schwartz, Ilan S.; Retief, Liezl; Bastos, Armanda D.S.; Matthee, Sonja; Preiser, Wolfgang; Bennett, Nigel Charles; Maphanga, Tsidiso; Govender, Nelesh P.; Colebunders, Robert; Kenyon, Chris

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dc.contributor.author	Cronje, Nadine
dc.contributor.author	Schwartz, Ilan S.
dc.contributor.author	Retief, Liezl
dc.contributor.author	Bastos, Armanda D.S.
dc.contributor.author	Matthee, Sonja
dc.contributor.author	Preiser, Wolfgang
dc.contributor.author	Bennett, Nigel Charles
dc.contributor.author	Maphanga, Tsidiso
dc.contributor.author	Govender, Nelesh P.
dc.contributor.author	Colebunders, Robert
dc.contributor.author	Kenyon, Chris
dc.date.accessioned	2018-10-09T10:53:00Z
dc.date.issued	2018-06
dc.description.abstract	The ecological niche of Emergomyces africanus (formerly Emmonsia species), a dimorphic fungus that causes an AIDS-related mycosis in South Africa, is unknown. We hypothesized that natural infection with E. africanus occurs in wild small mammals. Using molecular detection with primers specific for E. africanus, we examined 1402 DNA samples from 26 species of mole-rats, rodents, and insectivores trapped in South Africa that included 1324 lung, 37 kidney, and 41 liver specimens. DNA of E. africanus was not detected in any animals. We conclude that natural infection of wild small mammals in South Africa with E. africanus has not been proven.	en_ZA
dc.description.department	Mammal Research Institute	en_ZA
dc.description.department	Zoology and Entomology	en_ZA
dc.description.embargo	2019-06-01
dc.description.librarian	hj2018	en_ZA
dc.description.sponsorship	The Finds Wetenschappelijk Onderzoek - Slanderer. ISS was supported by the R. Samuel McLaughlin - Manitoba Medical Services Foundation and University of Manitoba Dean's Fellowship Fund; and a Marie Curie International Research Staff Exchange Scheme award.	en_ZA
dc.description.uri	https://academic.oup.com/mmy	en_ZA
dc.identifier.citation	Cronje, N., Schwartz, I.S., Retief, L. et al. 2018, 'Attempted molecular detection of the thermally dimorphic human fungal pathogen Emergomyces africanus in terrestrial small mammals in South Africa', Medical Mycology, vol. 56, no. 4, pp. 510-513.	en_ZA
dc.identifier.issn	1369-3786 (print)
dc.identifier.issn	1460-2709 (online)
dc.identifier.other	10.1093/mmy/myx065
dc.identifier.uri	http://hdl.handle.net/2263/66827
dc.language.iso	en	en_ZA
dc.publisher	Oxford University Press	en_ZA
dc.rights	© The Author(s) 2017. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology. This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Medical Mycology following peer review. The definitive publisher-authenticated version is : Attempted molecular detection of the thermally dimorphic human fungal pathogen Emergomyces africanus in terrestrial small mammals in South Africa, Medical Mycology, vol. 56, no. 4, pp. 510-513, 2018. doi : 10.1093/mmy/myx065, is available online at : https://academic.oup.com/mmy.	en_ZA
dc.subject	Emmonsiosis	en_ZA
dc.subject	Emmonsia	en_ZA
dc.subject	Emergomycosis	en_ZA
dc.subject	Animal	en_ZA
dc.subject	Ecology	en_ZA
dc.subject	Acquired immune deficiency syndrome (AIDS)	en_ZA
dc.subject	Lung	en_ZA
dc.subject	Mycoses	en_ZA
dc.subject	Chrysosporium	en_ZA
dc.subject	Deoxyribonucleic acid (DNA)	en_ZA
dc.subject	Insectivora	en_ZA
dc.subject	Mammals	en_ZA
dc.subject	Mole rat	en_ZA
dc.subject	Rodentia	en_ZA
dc.subject	South Africa (SA)	en_ZA
dc.subject	Infection	en_ZA
dc.subject	Kidney	en_ZA
dc.subject	Liver	en_ZA
dc.subject	Pathogenic organism	en_ZA
dc.subject	Dimorphic	en_ZA
dc.subject	Fungi	en_ZA
dc.title	Attempted molecular detection of the thermally dimorphic human fungal pathogen Emergomyces africanus in terrestrial small mammals in South Africa	en_ZA
dc.type	Postprint Article	en_ZA