Attempted molecular detection of the thermally dimorphic human fungal pathogen Emergomyces africanus in terrestrial small mammals in South Africa

dc.contributor.authorCronje, Nadine
dc.contributor.authorSchwartz, Ilan S.
dc.contributor.authorRetief, Liezl
dc.contributor.authorBastos, Armanda D.S.
dc.contributor.authorMatthee, Sonja
dc.contributor.authorPreiser, Wolfgang
dc.contributor.authorBennett, Nigel Charles
dc.contributor.authorMaphanga, Tsidiso
dc.contributor.authorGovender, Nelesh P.
dc.contributor.authorColebunders, Robert
dc.contributor.authorKenyon, Chris
dc.date.accessioned2018-10-09T10:53:00Z
dc.date.issued2018-06
dc.description.abstractThe ecological niche of Emergomyces africanus (formerly Emmonsia species), a dimorphic fungus that causes an AIDS-related mycosis in South Africa, is unknown. We hypothesized that natural infection with E. africanus occurs in wild small mammals. Using molecular detection with primers specific for E. africanus, we examined 1402 DNA samples from 26 species of mole-rats, rodents, and insectivores trapped in South Africa that included 1324 lung, 37 kidney, and 41 liver specimens. DNA of E. africanus was not detected in any animals. We conclude that natural infection of wild small mammals in South Africa with E. africanus has not been proven.en_ZA
dc.description.departmentMammal Research Instituteen_ZA
dc.description.departmentZoology and Entomologyen_ZA
dc.description.embargo2019-06-01
dc.description.librarianhj2018en_ZA
dc.description.sponsorshipThe Finds Wetenschappelijk Onderzoek - Slanderer. ISS was supported by the R. Samuel McLaughlin - Manitoba Medical Services Foundation and University of Manitoba Dean's Fellowship Fund; and a Marie Curie International Research Staff Exchange Scheme award.en_ZA
dc.description.urihttps://academic.oup.com/mmyen_ZA
dc.identifier.citationCronje, N., Schwartz, I.S., Retief, L. et al. 2018, 'Attempted molecular detection of the thermally dimorphic human fungal pathogen Emergomyces africanus in terrestrial small mammals in South Africa', Medical Mycology, vol. 56, no. 4, pp. 510-513.en_ZA
dc.identifier.issn1369-3786 (print)
dc.identifier.issn1460-2709 (online)
dc.identifier.other10.1093/mmy/myx065
dc.identifier.urihttp://hdl.handle.net/2263/66827
dc.language.isoenen_ZA
dc.publisherOxford University Pressen_ZA
dc.rights© The Author(s) 2017. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology. This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Medical Mycology following peer review. The definitive publisher-authenticated version is : Attempted molecular detection of the thermally dimorphic human fungal pathogen Emergomyces africanus in terrestrial small mammals in South Africa, Medical Mycology, vol. 56, no. 4, pp. 510-513, 2018. doi : 10.1093/mmy/myx065, is available online at : https://academic.oup.com/mmy.en_ZA
dc.subjectEmmonsiosisen_ZA
dc.subjectEmmonsiaen_ZA
dc.subjectEmergomycosisen_ZA
dc.subjectAnimalen_ZA
dc.subjectEcologyen_ZA
dc.subjectAcquired immune deficiency syndrome (AIDS)en_ZA
dc.subjectLungen_ZA
dc.subjectMycosesen_ZA
dc.subjectChrysosporiumen_ZA
dc.subjectDeoxyribonucleic acid (DNA)en_ZA
dc.subjectInsectivoraen_ZA
dc.subjectMammalsen_ZA
dc.subjectMole-ratsen_ZA
dc.subjectRodentiaen_ZA
dc.subjectSouth Africa (SA)en_ZA
dc.subjectInfectionen_ZA
dc.subjectKidneyen_ZA
dc.subjectLiveren_ZA
dc.subjectPathogenic organismen_ZA
dc.subjectDimorphicen_ZA
dc.subjectFungien_ZA
dc.titleAttempted molecular detection of the thermally dimorphic human fungal pathogen Emergomyces africanus in terrestrial small mammals in South Africaen_ZA
dc.typePostprint Articleen_ZA

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Cronje_Attempted_2018.pdf
Size:
247.82 KB
Format:
Adobe Portable Document Format
Description:
Postprint Article
Download

License bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.75 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Research Articles (Zoology and Entomology)
Research Articles (Mammal Research Institute)
Research Articles (University of Pretoria)
Simple item page