Enterovirus D68 and other enterovirus serotypes identified in South African patients with severe acute respiratory illness, 2009-2011
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Date
Authors
Hellferscee, Orienka
Treurnicht, Florette K.
Tempia, Stefano
Variava, Ebrahim
Dawood, Halima
Kahn, Kathleen
Cohen, Adam L.
Pretorius, Marthi Andréa
Cohen, Cheryl
Madhi, Shabir A.
Journal Title
Journal ISSN
Volume Title
Publisher
Wiley Open Access
Abstract
BACKGROUND : Human enteroviruses (EV) have been associated with severe acute respiratory
illness (SARI) in South Africa.
OBJECTIVES : We aimed to describe the molecular epidemiology of EV serotypes among
patients hospitalized with SARI during 2009-2011.
PATIENTS/METHODS : Study samples from patients were tested for the presence of enterovirus
using a polymerase chain reaction assay.
RESULTS : 8.2% (842/10 260) of SARI cases tested positive for enterovirus; 16% (7/45)
were species EV-A,
44% (20/45) EV-B,
18% (8/45) EV-C
and 22% (10/45) EV-D.
Seventeen different EV serotypes were identified within EV-A
to EV-D,
of which EV-D68
(22%; 10/45) and Echovirus 3 (11%; 5/45) were the most prevalent.
CONCLUSIONS : EV-D68
should be monitored in South Africa to assess the emergence of
highly pathogenic strains.
Description
Keywords
Enterovirus, EV-D68, Pneumonia, South Africa (SA), Human enterovirus (HEV), Severe acute respiratory illness (SARI)
Sustainable Development Goals
Citation
Hellferscee O, Treurnicht FK, Tempia
S, et al. Enterovirus D68 and other enterovirus serotypes
identified in South African patients with severe acute
respiratory illness, 2009–2011.
Influenza Other Respi Viruses.
2017;11:211–219. https://DOI.org/10.1111/irv.12444,