Enterovirus D68 and other enterovirus serotypes identified in South African patients with severe acute respiratory illness, 2009-2011

dc.contributor.authorHellferscee, Orienka
dc.contributor.authorTreurnicht, Florette K.
dc.contributor.authorTempia, Stefano
dc.contributor.authorVariava, Ebrahim
dc.contributor.authorDawood, Halima
dc.contributor.authorKahn, Kathleen
dc.contributor.authorCohen, Adam L.
dc.contributor.authorPretorius, Marthi Andréa
dc.contributor.authorCohen, Cheryl
dc.contributor.authorMadhi, Shabir A.
dc.contributor.authorVenter, Marietjie
dc.date.accessioned2018-01-24T05:18:59Z
dc.date.available2018-01-24T05:18:59Z
dc.date.issued2017-04
dc.description.abstractBACKGROUND : Human enteroviruses (EV) have been associated with severe acute respiratory illness (SARI) in South Africa. OBJECTIVES : We aimed to describe the molecular epidemiology of EV serotypes among patients hospitalized with SARI during 2009-2011. PATIENTS/METHODS : Study samples from patients were tested for the presence of enterovirus using a polymerase chain reaction assay. RESULTS : 8.2% (842/10 260) of SARI cases tested positive for enterovirus; 16% (7/45) were species EV-A, 44% (20/45) EV-B, 18% (8/45) EV-C and 22% (10/45) EV-D. Seventeen different EV serotypes were identified within EV-A to EV-D, of which EV-D68 (22%; 10/45) and Echovirus 3 (11%; 5/45) were the most prevalent. CONCLUSIONS : EV-D68 should be monitored in South Africa to assess the emergence of highly pathogenic strains.en_ZA
dc.description.departmentMedical Virologyen_ZA
dc.description.librarianam2018en_ZA
dc.description.sponsorshipThe United States Centers for Disease Control and Prevention, Atlanta, Georgia, USA (co-operative agreement number: 5U51IP000155).en_ZA
dc.description.urihttp://www.wileyonlinelibrary.com/journal/irven_ZA
dc.description.urihttp://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1750-2659en_ZA
dc.identifier.citationHellferscee O, Treurnicht FK, Tempia S, et al. Enterovirus D68 and other enterovirus serotypes identified in South African patients with severe acute respiratory illness, 2009–2011. Influenza Other Respi Viruses. 2017;11:211–219. https://DOI.org/10.1111/irv.12444,en_ZA
dc.identifier.issn1750-2640 (print)
dc.identifier.issn1750-2659 (online)
dc.identifier.other10.1111/irv.12444
dc.identifier.urihttp://hdl.handle.net/2263/63700
dc.language.isoenen_ZA
dc.publisherWiley Open Accessen_ZA
dc.rights© 2017 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.en_ZA
dc.subjectEnterovirusen_ZA
dc.subjectEV-D68en_ZA
dc.subjectPneumoniaen_ZA
dc.subjectSouth Africa (SA)en_ZA
dc.subjectHuman enterovirus (HEV)en_ZA
dc.subjectSevere acute respiratory illness (SARI)en_ZA
dc.titleEnterovirus D68 and other enterovirus serotypes identified in South African patients with severe acute respiratory illness, 2009-2011en_ZA
dc.typeArticleen_ZA

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