Systemic lupus erythematosus : a possible cause of non-alcoholic Wernicke’s encephalopathy

Show simple item record Nyo, M.T.L. Magazi, D. Ally, Mahmood Moosa Tar Mahomed 2017-09-11T11:18:02Z 2017-09-11T11:18:02Z 2017-04
dc.description.abstract We report a young woman with systemic lupus erythematosus (SLE) and an acute cerebellar ataxia. A history of poor appetite and vomiting preceded the inco-ordination. Ataxia in SLE has been well described, but is nevertheless uncommon. The clinical triad of mild confusion, ataxia and ophthalmoplegia also raised the possibility of Wernicke’s encephalopathy (WE). The diagnosis of WE was further supported by the magnetic resonance imaging features. Owing to overlapping causal factors, this case illustrates the complexity of diagnosing and managing neuropsychiatric syndromes in a patient with SLE. The limited published literature on SLE-related cerebellar syndromes adds to the challenge. Gastrointestinal manifestations of SLE are described as being common in SLE, with nausea and vomiting occurring in >50% of cases in some series. Poor eating habits and vomiting are well-described causes of non-alcoholic WE. This is the first description of gastrointestinal SLE as a possible cause of WE. en_ZA
dc.description.department Internal Medicine en_ZA
dc.description.librarian am2017 en_ZA
dc.description.uri en_ZA
dc.identifier.citation Nyo, M.T.L., Magazi, D. & Ally, M.M.T.M. 2017, 'Systemic lupus erythematosus : a possible cause of non-alcoholic Wernicke’s encephalopathy', South African Medical Journal, vol. 107, no. 4, pp. 299-301. en_ZA
dc.identifier.issn 0256-9574 (print)
dc.identifier.issn 2078-5135 (online)
dc.identifier.other 10.7196/SAMJ.2017.v107i4.12053
dc.language.iso en en_ZA
dc.publisher Health and Medical Publishing Group en_ZA
dc.rights © 2017 Health & Medical Publishing Group. This article is licensed under a Creative Commons Attribution-NonCommercial Works License (CC BY-NC 3.0). en_ZA
dc.subject Vomiting en_ZA
dc.subject Systemic lupus erythematosus (SLE) en_ZA
dc.subject Acute cerebellar ataxia en_ZA
dc.subject Poor appetite en_ZA
dc.subject Inco-ordination en_ZA
dc.subject Wernicke’s encephalopathy (WE) en_ZA
dc.title Systemic lupus erythematosus : a possible cause of non-alcoholic Wernicke’s encephalopathy en_ZA
dc.type Article en_ZA

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