Systemic lupus erythematosus : a possible cause of non-alcoholic Wernicke’s encephalopathy

dc.contributor.authorNyo, M.T.L.
dc.contributor.authorMagazi, D.
dc.contributor.authorAlly, Mahmood Moosa Tar Mahomed
dc.date.accessioned2017-09-11T11:18:02Z
dc.date.available2017-09-11T11:18:02Z
dc.date.issued2017-04
dc.description.abstractWe report a young woman with systemic lupus erythematosus (SLE) and an acute cerebellar ataxia. A history of poor appetite and vomiting preceded the inco-ordination. Ataxia in SLE has been well described, but is nevertheless uncommon. The clinical triad of mild confusion, ataxia and ophthalmoplegia also raised the possibility of Wernicke’s encephalopathy (WE). The diagnosis of WE was further supported by the magnetic resonance imaging features. Owing to overlapping causal factors, this case illustrates the complexity of diagnosing and managing neuropsychiatric syndromes in a patient with SLE. The limited published literature on SLE-related cerebellar syndromes adds to the challenge. Gastrointestinal manifestations of SLE are described as being common in SLE, with nausea and vomiting occurring in >50% of cases in some series. Poor eating habits and vomiting are well-described causes of non-alcoholic WE. This is the first description of gastrointestinal SLE as a possible cause of WE.en_ZA
dc.description.departmentInternal Medicineen_ZA
dc.description.librarianam2017en_ZA
dc.description.urihttp://www.samj.org.zaen_ZA
dc.identifier.citationNyo, M.T.L., Magazi, D. & Ally, M.M.T.M. 2017, 'Systemic lupus erythematosus : a possible cause of non-alcoholic Wernicke’s encephalopathy', South African Medical Journal, vol. 107, no. 4, pp. 299-301.en_ZA
dc.identifier.issn0256-9574 (print)
dc.identifier.issn2078-5135 (online)
dc.identifier.other10.7196/SAMJ.2017.v107i4.12053
dc.identifier.urihttp://hdl.handle.net/2263/62223
dc.language.isoenen_ZA
dc.publisherHealth and Medical Publishing Groupen_ZA
dc.rights© 2017 Health & Medical Publishing Group. This article is licensed under a Creative Commons Attribution-NonCommercial Works License (CC BY-NC 3.0).en_ZA
dc.subjectVomitingen_ZA
dc.subjectSystemic lupus erythematosus (SLE)en_ZA
dc.subjectAcute cerebellar ataxiaen_ZA
dc.subjectPoor appetiteen_ZA
dc.subjectInco-ordinationen_ZA
dc.subjectWernicke’s encephalopathy (WE)en_ZA
dc.titleSystemic lupus erythematosus : a possible cause of non-alcoholic Wernicke’s encephalopathyen_ZA
dc.typeArticleen_ZA

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