dc.contributor.author |
Dutta, Jyotibon
|
|
dc.contributor.author |
Naicker, Tricia
|
|
dc.contributor.author |
Ebenhan, Thomas
|
|
dc.contributor.author |
Kruger, Hendrik G.
|
|
dc.contributor.author |
Arvidsson, Per I.
|
|
dc.contributor.author |
Govender, Thavendran
|
|
dc.date.accessioned |
2017-07-19T07:28:36Z |
|
dc.date.issued |
2017-06 |
|
dc.description.abstract |
This present review provides an account on the available synthetic strategies employed to radiolabel commercial and potential bacteria-selective probes fortomographic imaging. These molecular probes encompass leukocytes, antibodies, small molecules, peptides, antibiotics, macrolides, vitamins, oligomers and siderophores. Although this technique has shown to be a valuable tool for non-invasive infection imaging, more development is required to create easy-to-radiolabel kit solutions procedures for the preparation of the probes. |
en_ZA |
dc.description.department |
Nuclear Medicine |
en_ZA |
dc.description.embargo |
2018-06-16 |
|
dc.description.librarian |
hj2017 |
en_ZA |
dc.description.uri |
http://www.elsevier.com/locate/ejmech |
en_ZA |
dc.identifier.citation |
Dutta, J., Naicker, T., Ebenhan, T., Kruger, H.G., Arvidsson, P.I. & Govender, T. 2017, 'Synthetic approaches to radiochemical probes for imaging of bacterial infections', European Journal of Medicinal Chemistry, vol. 133, pp. 287-308. |
en_ZA |
dc.identifier.issn |
1768-3254 (online |
|
dc.identifier.issn |
0223-5234 (print) |
|
dc.identifier.other |
10.1016/j.ejmech.2017.03.060 |
|
dc.identifier.uri |
http://hdl.handle.net/2263/61374 |
|
dc.language.iso |
en |
en_ZA |
dc.publisher |
Elsevier |
en_ZA |
dc.rights |
© 2017 Elsevier Masson SAS. All rights reserved. Notice : this is the author’s version of a work that was accepted for publication in European Journal of Medicinal Chemistry. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. A definitive version was subsequently published in European Journal of Medicinal Chemistry, vol. 133, pp. 287-308, 2017. doi : 10.1016/j.ejmech.2017.03.060. |
en_ZA |
dc.subject |
White cell scintigraphy |
en_ZA |
dc.subject |
Staphylococcus-aureus infection |
en_ZA |
dc.subject |
Inflammatory-bowel-disease |
en_ZA |
dc.subject |
Colloid-labeled-leukocytes |
en_ZA |
dc.subject |
Antimicrobial peptide (AMP) |
en_ZA |
dc.subject |
Escherichia coli |
en_ZA |
dc.subject |
In-vitro |
en_ZA |
dc.subject |
Biologival evaluation |
en_ZA |
dc.subject |
Mycobacterium tuberculosis (MTB) |
en_ZA |
dc.subject |
Positron emission tomography (PET) |
en_ZA |
dc.title |
Synthetic approaches to radiochemical probes for imaging of bacterial infections |
en_ZA |
dc.type |
Postprint Article |
en_ZA |