The microbiome in chronic inflammatory airway disease : a threatened species

Show simple item record Green, Robin J. Van Niekerk, Andre Jeevarathnum, A.C. Feldman, Charles Richards, Guy A. 2016-08-23T12:40:18Z 2016-08-23T12:40:18Z 2016-08
dc.description.abstract The human body is exposed to a multitude of microbes and infectious organisms throughout life. Many of these organisms colonise the skin, gastrointestinal tract (GIT) and airway. We now recognise that this colonisation includes the lower airway, previously thought to be sterile. These colonising organisms play an important role in disease prevention, including an array of chronic inflammatory conditions that are unrelated to infectious diseases. However, new evidence of immune dysregulation suggests that early colonisation, especially of the GIT and airway, by pathogenic micro-organisms, has deleterious effects that may contribute to the potential to induce chronic inflammation in young children, which may only express itself in adult life. en_ZA
dc.description.department Paediatrics and Child Health en_ZA
dc.description.librarian am2016 en_ZA
dc.description.sponsorship The South African Allergic Rhinitis Working Group is an independent organisation. An annual meeting is supported by an unrestricted educational grant from Aspen Pharma en_ZA
dc.description.uri en_ZA
dc.identifier.citation Green, RJ, Van Niekerk, A, Jeevarathnum, AC, Feldman, C & Richards, GA 2016, 'The microbiome in chronic inflammatory airway disease : a threatened species', South African Medical Journal, vol. 106, no. 8, pp. 779-781. en_ZA
dc.identifier.issn 0256-9574 (print)
dc.identifier.issn 2078-5135 (online)
dc.identifier.other 10.7196/SAMJ.2016.v106i8.11159
dc.language.iso en en_ZA
dc.publisher Health and Medical Publishing Group en_ZA
dc.rights © 2016 Health & Medical Publishing Group. This work is licensed under a Creative Commons Attribution-NonCommercial Works License (CC BY-NC 3.0). en_ZA
dc.subject Disease prevention en_ZA
dc.subject Gastrointestinal tract (GIT) en_ZA
dc.subject Chronic inflammation en_ZA
dc.subject Airway en_ZA
dc.subject Microbiome en_ZA
dc.subject Infectious organisms en_ZA
dc.subject Colonising organisms en_ZA
dc.title The microbiome in chronic inflammatory airway disease : a threatened species en_ZA
dc.type Article en_ZA

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