Light and electron microscopical studies on canine encephalitozoonosis : cerebral vasculitis

Show simple item record Van Dellen, A.F. Botha, W.S. Warnes, W.E.J. Boomker, Jacob Diederik Frederik
dc.contributor.editor Bigalke, R.D.
dc.contributor.editor Cameron, Colin McKenzie
dc.contributor.editor Gilchrist, Frances M.C.
dc.contributor.editor Morren, A.J.
dc.contributor.editor Verster, Anna J.M.
dc.contributor.editor Verwoerd, Daniel Wynand
dc.contributor.editor Walker, Jane B.
dc.contributor.other De Kock, V.E. 2016-07-07T07:50:10Z 2016-07-07T07:50:10Z 2016 1978
dc.description The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. en_ZA
dc.description.abstract Brain lesions in 2 natural cases of canine encephalitozoonosis were studied by light and electron microscopy. Granulomatous reactions, associated with small vessels and capillaries, partly originated from extensive perithelial cell proliferation which ultimately produced the epithelioid cell component. Diffuse glial reactions apparently occurred in relation to the vasculitis. Lymphoid cells infiltrated the epithelioid and glial cell inflammation. Encephalitozoon in all its reproductive stages was identified as the aetiological agent, and ultrastructurally differentiated from Nosema on the basis that a single nucleus was observed. Viable organisms were present only within endothelial cells. Macrophages containing dead spores were usually seen around parasitized vessels and, less frequently, in them neuropil. Organisms, whether viable or non-viable, were never seen extracellularly at the ultrastructural level. Selected histochemical stains and electron microscopy were used to differentiate between viable and non-viable spores. Vasculitis is demonstrated as the underlying lesion of canine encephalitozoonosism affecting the brain and is suggested to be the basic factor in the pathogenesis of this disease. en_ZA
dc.identifier.citation Van Dellen, AF Botha, WS, Boomker, J & Warnes, WEJ 1978, 'Light and electron microscopical studies on canine encephalitozoonosis : cerebral vasculitis’, Onderstepoort Journal of Veterinary Research, vol. 45, no. 3, pp. 165-186. en_ZA
dc.identifier.issn 0330-2465
dc.language.iso en en_ZA
dc.publisher Pretoria : The Government Printer en_ZA
dc.rights © 1978 ARC – Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). © 2016 University of Pretoria. Department of Library Services (digital). en_ZA
dc.subject Veterinary medicine en_ZA
dc.subject.lcsh Veterinary medicine -- South Africa
dc.subject.lcsh Dogs -- Diseases en_ZA
dc.title Light and electron microscopical studies on canine encephalitozoonosis : cerebral vasculitis en_ZA
dc.type Article en_ZA

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