Immunogenicity and pathogenicity of three South African strains of Babesia bovis in Bos indicus cattle
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Date
Authors
De Vos, A.J.
Journal Title
Journal ISSN
Volume Title
Publisher
Pretoria : The Government Printer
Abstract
A strain of Babesia bovis, which has been routinely used in the locally produced babesiosis vaccine for two decades and maintained by needle passage, was of low virulence and therefore safe, but it induced poor protection to challenge with two field isolates. Animals infected with this attenuated strain and subsequently challenged heterologously with a field strain were solidly immune when challenged later with a second field strain. The two field strains, though more virulent, conferred a high degree of immunity to heterologous challenge.
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Keywords
Babesia bovis
Sustainable Development Goals
Citation
De Vos, AJ 1978, 'Immunogenicity and pathogenicity of three South African strains of Babesia bovis in Bos indicus cattle.’, Onderstepoort Journal of Veterinary Research, vol. 45, no. 2, pp. 119-124.