Immunogenicity and pathogenicity of three South African strains of Babesia bovis in Bos indicus cattle

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Date

Authors

De Vos, A.J.

Journal Title

Journal ISSN

Volume Title

Publisher

Pretoria : The Government Printer

Abstract

A strain of Babesia bovis, which has been routinely used in the locally produced babesiosis vaccine for two decades and maintained by needle passage, was of low virulence and therefore safe, but it induced poor protection to challenge with two field isolates. Animals infected with this attenuated strain and subsequently challenged heterologously with a field strain were solidly immune when challenged later with a second field strain. The two field strains, though more virulent, conferred a high degree of immunity to heterologous challenge.

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Keywords

Babesia bovis

Sustainable Development Goals

Citation

De Vos, AJ 1978, 'Immunogenicity and pathogenicity of three South African strains of Babesia bovis in Bos indicus cattle.’, Onderstepoort Journal of Veterinary Research, vol. 45, no. 2, pp. 119-124.