Acute viral bronchiolitis in South Africa : strategies for management and prevention

Show simple item record Zar, Heather J. Madhi, S.A. White, D.A. Masekela, R. Risenga, S. Lewis, H. Feldman, Charles Morrow, B. Jeena, P. 2016-05-30T05:16:40Z 2016-05-30T05:16:40Z 2016-04
dc.description.abstract Management of acute viral bronchiolitis is largely supportive. There is currently no proven effective therapy other than oxygen for hypoxic children. The evidence indicates that there is no routine benefit from inhaled, rapid short-acting bronchodilators, adrenaline or ipratropium bromide for children with acute viral bronchiolitis. Likewise, there is no demonstrated benefit from routine use of inhaled or oral corticosteroids, inhaled hypertonic saline nebulisation, montelukast or antibiotics. The last should be reserved for children with severe disease, when bacterial co-infection is suspected. Prevention of respiratory syncytial virus (RSV) disease remains a challenge. A specific RSV monoclonal antibody, palivizumab, administered as an intramuscular injection, is available for children at risk of severe bronchiolitis, including premature infants, young children with chronic lung disease, immunodeficiency, or haemodynamically significant congenital heart disease. Prophylaxis should be commenced at the start of the RSV season and given monthly during the season. The development of an RSV vaccine may offer a more effective alternative to prevent disease, for which the results of clinical trials are awaited. Education of parents or caregivers and healthcare workers about diagnostic and management strategies should include the following: bronchiolitis is caused by a virus; it is seasonal; it may start as an upper respiratory tract infection with low-grade fever; symptoms are cough and wheeze, often with fast breathing; antibiotics are generally not needed; and the condition is usually self limiting, although symptoms may occur for up to 4 weeks in some children. en_ZA
dc.description.department Paediatrics and Child Health en_ZA
dc.description.librarian am2016 en_ZA
dc.description.uri en_ZA
dc.identifier.citation Zar, HJ, Madhi, SA, White, DA, Masekela, R, Risenga, S, Lewis, H, Feldman, C, Morrow, B & Jeena, P 2016, 'Acute viral bronchiolitis in South Africa : strategies for management and prevention', South African Medical Journal, vol. 106, no. 4, pp. 330-332. en_ZA
dc.identifier.issn 0256-9574 (print)
dc.identifier.issn 2078-5135 (online)
dc.identifier.other 10.7196/SAMJ.2016.v106i4.10437
dc.language.iso en en_ZA
dc.publisher Health and Medical Publishing Group en_ZA
dc.rights © 2016 Health & Medical Publishing Group. This work is licensed under a Creative Commons Attribution-NonCommercial Works License (CC BY-NC 3.0). en_ZA
dc.subject Children en_ZA
dc.subject Therapy en_ZA
dc.subject Acute viral bronchiolitis en_ZA
dc.subject Respiratory syncytial virus (RSV) en_ZA
dc.title Acute viral bronchiolitis in South Africa : strategies for management and prevention en_ZA
dc.type Article en_ZA

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