ARV options in drug resistance

Show simple item record Rossouw, Theresa M. 2016-05-11T13:03:46Z 2016-05-11T13:03:46Z 2016-01
dc.description.abstract Antiretroviral treatment (ART) has dramatically changed the course of (HIV) infection, allowing for control of the virus in the peripheral circulation, significant reconstitution of the immune system and achievement of near-normal life expectancy. Similar to other antimicrobial agents, the efficacy of ART is, however, curtailed by the development of drug resistance. Resistance can either be transmitted from an infected partner/mother or acquired through inadequate drug pressure, usually caused by suboptimal adherence, treatment interruptions, improper treatment regimens, impaired drug absorption or drug interactions. Of these, adherence problems are by far the most common cause and remain a significant obstacle to achieving lifelong virological control. en_ZA
dc.description.department Family Medicine en_ZA
dc.description.department Immunology en_ZA
dc.description.librarian am2016 en_ZA
dc.description.uri en_ZA
dc.identifier.citation Rossouw, TM 2016, 'ARV options in drug resistance', Medical Chronicle, Dec/Jan 2016, pp. 24. en_ZA
dc.language.iso en en_ZA
dc.publisher New Media Publishing en_ZA
dc.rights New Media Publishing (Pty) Ltd. en_ZA
dc.subject Drug resistance en_ZA
dc.subject Virological control en_ZA
dc.subject Infection en_ZA
dc.subject Antiretroviral treatment (ART) en_ZA
dc.subject Human immunodeficiency virus (HIV) en_ZA
dc.title ARV options in drug resistance en_ZA
dc.type Article en_ZA

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