ARV options in drug resistance

dc.contributor.authorRossouw, Theresa M.
dc.date.accessioned2016-05-11T13:03:46Z
dc.date.available2016-05-11T13:03:46Z
dc.date.issued2016-01
dc.description.abstractAntiretroviral treatment (ART) has dramatically changed the course of (HIV) infection, allowing for control of the virus in the peripheral circulation, significant reconstitution of the immune system and achievement of near-normal life expectancy. Similar to other antimicrobial agents, the efficacy of ART is, however, curtailed by the development of drug resistance. Resistance can either be transmitted from an infected partner/mother or acquired through inadequate drug pressure, usually caused by suboptimal adherence, treatment interruptions, improper treatment regimens, impaired drug absorption or drug interactions. Of these, adherence problems are by far the most common cause and remain a significant obstacle to achieving lifelong virological control.en_ZA
dc.description.departmentFamily Medicineen_ZA
dc.description.departmentImmunologyen_ZA
dc.description.librarianam2016en_ZA
dc.description.urihttp://www.medicalchronicle.co.zaen_ZA
dc.identifier.citationRossouw, TM 2016, 'ARV options in drug resistance', Medical Chronicle, Dec/Jan 2016, pp. 24.en_ZA
dc.identifier.urihttp://hdl.handle.net/2263/52570
dc.language.isoenen_ZA
dc.publisherNew Media Publishingen_ZA
dc.rightsNew Media Publishing (Pty) Ltd.en_ZA
dc.subjectDrug resistanceen_ZA
dc.subjectVirological controlen_ZA
dc.subjectInfectionen_ZA
dc.subjectAntiretroviral treatment (ART)en_ZA
dc.subjectHuman immunodeficiency virus (HIV)en_ZA
dc.subject.otherHealth sciences articles SDG-03
dc.subject.otherSDG-03: Good health and well-being
dc.titleARV options in drug resistanceen_ZA
dc.typeArticleen_ZA

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