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Browsing Research Articles (Mammal Research Institute) by Subject "Gemcitabine"

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GnRH-gemcitabine conjugates for the treatment of androgen-independent prostate cancer : pharmacokinetic enhancements combined with targeted drug delivery

Karampelas, Theodoros; Argyros, Orestis; Sayyad, Nisar; Spyridaki, Katerina; Pappas, Charalampos; Morgan, Kevin; Kolios, George; Millar, Robert P.; Liapakis, George; Tzakos, Andreas G.; Fokas, Demosthenes; Tamvakopoulos, Constantin (American Chemical Society, 2014-04)

Gemcitabine, a drug with established efficacy against a number of solid tumors, has therapeutic limitations due to its rapid metabolic inactivation. The aim of this study was the development of an innovative strategy to ...

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