Diverse sapovirus genotypes identified in children hospitalised with gastroenteritis in selected regions of South Africa

Murray, Tanya Y.; Nadan, Sandrama; Page, Nicola Anne; Taylor, Maureen B.

dc.contributor.author	Murray, Tanya Y.
dc.contributor.author	Nadan, Sandrama
dc.contributor.author	Page, Nicola Anne
dc.contributor.author	Taylor, Maureen B.
dc.date.accessioned	2016-05-03T10:32:03Z
dc.date.issued	2016-03
dc.description.abstract	BACKGROUND : Sapoviruses (SaVs) are recognised as causative agents of gastroenteritis worldwide. How-ever, data on the genetic diversity of this virus in Africa are lacking, particularly in the form of currentlong-term studies. OBJECTIVE : To determine the genetic diversity of SaVs in children hospitalised with gastroenteritis in SouthAfrica (SA). STUDY DESIGN : From April 2009 to December 2013, SaVs were characterised from stool specimens fromchildren hospitalised with gastroenteritis in four provinces of SA.RESULTS : Fourteen different SaV genotypes were identified from the 221 strains that were characterised.Genogroup (G) IV predominated overall and was detected in 24% (53/221) of specimens. The other iden-tified genotypes included six belonging to GI (GI.1–GI.3, GI.5, GI.6, and GI.7) and seven belonging to GII(GII.1–GII.7). CONCLUSION : This study has provided the first comprehensive data on the genetic diversity of SaVs in aclinical setting in SA, contributing to the global knowledge of this virus.	en_ZA
dc.description.department	Medical Virology	en_ZA
dc.description.embargo	2017-03-31
dc.description.librarian	hb2016	en_ZA
dc.description.uri	http://www.elsevier.com/locate/jcv	en_ZA
dc.identifier.citation	Murray, TY, Nadan, S, Page, NA & Taylor, MB 2016, 'Diverse sapovirus genotypes identified in children hospitalised with gastroenteritis in selected regions of South Africa', Journal of Clinical Virology, vol. 76, no. 1, pp. 24-29.	en_ZA
dc.identifier.issn	0929-1873 (print)
dc.identifier.issn	1573-8469 (online)
dc.identifier.other	10.1016/j.jcv.2016.01.003
dc.identifier.uri	http://hdl.handle.net/2263/52236
dc.language.iso	en	en_ZA
dc.publisher	Elsevier	en_ZA
dc.rights	© 2016 Elsevier B.V. All rights reserved. Notice : this is the author’s version of a work that was accepted for publication in Journal of Clinical Virology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of Clinical Virology, vol. 76, no.1, pp. 24-29, 2016. doi : 10.1016/j.jcv.2016.01.003.	en_ZA
dc.subject	Genotyping	en_ZA
dc.subject	Molecular diversity	en_ZA
dc.subject	Paediatric	en_ZA
dc.subject	South Africa (SA)	en_ZA
dc.subject	Sapoviruses (SaVs)	en_ZA
dc.title	Diverse sapovirus genotypes identified in children hospitalised with gastroenteritis in selected regions of South Africa	en_ZA
dc.type	Postprint Article	en_ZA