Diverse sapovirus genotypes identified in children hospitalised with gastroenteritis in selected regions of South Africa
| dc.contributor.author | Murray, Tanya Y. | |
| dc.contributor.author | Nadan, Sandrama | |
| dc.contributor.author | Page, Nicola Anne | |
| dc.contributor.author | Taylor, Maureen B. | |
| dc.contributor.email | maureen.taylor@up.ac.za | en_ZA |
| dc.date.accessioned | 2016-05-03T10:32:03Z | |
| dc.date.issued | 2016-03 | |
| dc.description.abstract | BACKGROUND : Sapoviruses (SaVs) are recognised as causative agents of gastroenteritis worldwide. How-ever, data on the genetic diversity of this virus in Africa are lacking, particularly in the form of currentlong-term studies. OBJECTIVE : To determine the genetic diversity of SaVs in children hospitalised with gastroenteritis in SouthAfrica (SA). STUDY DESIGN : From April 2009 to December 2013, SaVs were characterised from stool specimens fromchildren hospitalised with gastroenteritis in four provinces of SA.RESULTS : Fourteen different SaV genotypes were identified from the 221 strains that were characterised.Genogroup (G) IV predominated overall and was detected in 24% (53/221) of specimens. The other iden-tified genotypes included six belonging to GI (GI.1–GI.3, GI.5, GI.6, and GI.7) and seven belonging to GII(GII.1–GII.7). CONCLUSION : This study has provided the first comprehensive data on the genetic diversity of SaVs in aclinical setting in SA, contributing to the global knowledge of this virus. | en_ZA |
| dc.description.department | Medical Virology | en_ZA |
| dc.description.embargo | 2017-03-31 | |
| dc.description.librarian | hb2016 | en_ZA |
| dc.description.uri | http://www.elsevier.com/locate/jcv | en_ZA |
| dc.identifier.citation | Murray, TY, Nadan, S, Page, NA & Taylor, MB 2016, 'Diverse sapovirus genotypes identified in children hospitalised with gastroenteritis in selected regions of South Africa', Journal of Clinical Virology, vol. 76, no. 1, pp. 24-29. | en_ZA |
| dc.identifier.issn | 0929-1873 (print) | |
| dc.identifier.issn | 1573-8469 (online) | |
| dc.identifier.other | 10.1016/j.jcv.2016.01.003 | |
| dc.identifier.uri | http://hdl.handle.net/2263/52236 | |
| dc.language.iso | en | en_ZA |
| dc.publisher | Elsevier | en_ZA |
| dc.rights | © 2016 Elsevier B.V. All rights reserved. Notice : this is the author’s version of a work that was accepted for publication in Journal of Clinical Virology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of Clinical Virology, vol. 76, no.1, pp. 24-29, 2016. doi : 10.1016/j.jcv.2016.01.003. | en_ZA |
| dc.subject | Genotyping | en_ZA |
| dc.subject | Molecular diversity | en_ZA |
| dc.subject | Paediatric | en_ZA |
| dc.subject | South Africa (SA) | en_ZA |
| dc.subject | Sapoviruses (SaVs) | en_ZA |
| dc.title | Diverse sapovirus genotypes identified in children hospitalised with gastroenteritis in selected regions of South Africa | en_ZA |
| dc.type | Postprint Article | en_ZA |