Investigation of multidrug-resistant fatal colisepticaemia in weanling pigs

Show simple item record Fasina, Folorunso Oludayo Bwala, Dauda Garba Madoroba, Evelyn 2016-02-26T05:29:27Z 2016-02-26T05:29:27Z 2015-11-27
dc.description.abstract Escherichia coli is usually a benign commensal of the gut microflora. However, when E. coli acquires virulence genes it can multiply rapidly and cause disease through colonisation of the intestinal mucosa. Escherichia coli can become a significant pathogen in young pigs. We report an investigation of fatal colisepticaemia in weanling pigs from emerging farms where piglets and weaners were diarrhoeic and the mortality rate ranged between 15% and 70% in each litter. Faecal and tissue samples were processed for histopathology, bacteriology and molecular biology (multiplex and monoplex polymerase chain reaction) and we recovered enteroaggregative multidrug-resistant E. coli producing EAST-1 enterotoxin. An association between poor housing conditions and the observed cases was established and future management programmes were recommended to reduce the impact of such pathogens. Enteroaggregative E. coli is becoming a major problem in the pig industry. It therefore becomes necessary to establish the full impact of E. coli on the South African pig industry and to determine the geographic extent of the problem. en_ZA
dc.description.librarian am2015 en_ZA
dc.description.librarian ab2016
dc.description.uri en_ZA
dc.identifier.citation Fasina, F.O., Bwala, D.G. & Madoroba, E., 2015, ‘Investigation of multidrug-resistant fatal colisepticaemia in weanling pigs’, Onderstepoort Journal of Veterinary Research 82(1), Art. #986, 6 pages. http:// 10.4102/ojvr.v82i1.986. en_ZA
dc.identifier.issn 0030-2465 (print)
dc.identifier.issn 2219-0635 (online)
dc.identifier.other 10.4102/ojvr.v82i1.986
dc.identifier.other H-9699-2013
dc.identifier.other 16416667800
dc.language.iso en en_ZA
dc.publisher AOSIS Open Journals en_ZA
dc.relation.requires Adobe Acrobat Reader en
dc.rights © 2015. The Authors. Licensee: AOSIS OpenJournals. This work is licensed under the Creative Commons Attribution License. en_ZA
dc.subject Escherichia coli en_ZA
dc.subject Virulence genes en_ZA
dc.subject Pigs -- Diseases en_ZA
dc.subject South African pig industry en_ZA
dc.title Investigation of multidrug-resistant fatal colisepticaemia in weanling pigs en_ZA
dc.type Article en_ZA

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