Investigation of multidrug-resistant fatal colisepticaemia in weanling pigs

dc.contributor.authorFasina, Folorunso Oludayo
dc.contributor.authorBwala, Dauda Garba
dc.contributor.authorMadoroba, Evelyn
dc.contributor.emaildayo.fasina@up.ac.zaen_ZA
dc.date.accessioned2016-02-26T05:29:27Z
dc.date.available2016-02-26T05:29:27Z
dc.date.issued2015-11-27
dc.description.abstractEscherichia coli is usually a benign commensal of the gut microflora. However, when E. coli acquires virulence genes it can multiply rapidly and cause disease through colonisation of the intestinal mucosa. Escherichia coli can become a significant pathogen in young pigs. We report an investigation of fatal colisepticaemia in weanling pigs from emerging farms where piglets and weaners were diarrhoeic and the mortality rate ranged between 15% and 70% in each litter. Faecal and tissue samples were processed for histopathology, bacteriology and molecular biology (multiplex and monoplex polymerase chain reaction) and we recovered enteroaggregative multidrug-resistant E. coli producing EAST-1 enterotoxin. An association between poor housing conditions and the observed cases was established and future management programmes were recommended to reduce the impact of such pathogens. Enteroaggregative E. coli is becoming a major problem in the pig industry. It therefore becomes necessary to establish the full impact of E. coli on the South African pig industry and to determine the geographic extent of the problem.en_ZA
dc.description.librarianam2015en_ZA
dc.description.librarianab2016
dc.description.urihttp://www.ojvr.orgen_ZA
dc.identifier.citationFasina, F.O., Bwala, D.G. & Madoroba, E., 2015, ‘Investigation of multidrug-resistant fatal colisepticaemia in weanling pigs’, Onderstepoort Journal of Veterinary Research 82(1), Art. #986, 6 pages. http:// dx.DOI.org/ 10.4102/ojvr.v82i1.986.en_ZA
dc.identifier.issn0030-2465 (print)
dc.identifier.issn2219-0635 (online)
dc.identifier.other10.4102/ojvr.v82i1.986
dc.identifier.otherH-9699-2013
dc.identifier.other16416667800
dc.identifier.urihttp://hdl.handle.net/2263/51566
dc.language.isoenen_ZA
dc.publisherAOSIS Open Journalsen_ZA
dc.relation.requiresAdobe Acrobat Readeren
dc.rights© 2015. The Authors. Licensee: AOSIS OpenJournals. This work is licensed under the Creative Commons Attribution License.en_ZA
dc.subjectEscherichia colien_ZA
dc.subjectVirulence genesen_ZA
dc.subjectPigs -- Diseasesen_ZA
dc.subjectSouth African pig industryen_ZA
dc.titleInvestigation of multidrug-resistant fatal colisepticaemia in weanling pigsen_ZA
dc.typeArticleen_ZA

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