Abstract:
Mice can be passively protected against infection with Corynebacterium pseudotuberculosis with hyperimmune
rabbit serum prepared against whole bacterial cells. The mechanism of immunity depends on
the inhibition of secondary multiplication of the bacteria, not on antitoxic activity or enhanced phagocytosis
and destruction.
Passive transfer of macrophages obtained from mice immunized with inactivated vaccine to susceptible
mice which were subsequently challenged showed that the macrophages have no specific immunizing
properties.
