Formulation of an effective Pasteurella multocida vaccine for sheep
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Date
Authors
Cameron, Colin McKenzie
Bester, Faith J.
Journal Title
Journal ISSN
Volume Title
Publisher
Published by The Government Printer, Pretoria
Abstract
An effective vaccine for the immunization of sheep against Pasteurella multocida infection was prepared from P. multocida Strain D4 (Type D) and a selected strain of P. multocida Type A. Provided an adequate concentration of bacteria was used, the vaccine thus formulated induced antibodies in sheep that protected mice not only against the vaccine strains but also against infection by a number of heterologous Type A and Type D strains as well as untypable strains. A locally prepared A1(OH)₃ gel was found to be an effective adjuvant.
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Keywords
Veterinary medicine
Sustainable Development Goals
Citation
Cameron, CM & Bester, FJ 1984, 'Formulation of an effective Pasteurella multocida vaccine for sheep', Onderstepoort Journal of Veterinary Research, vol. 51, no. 3, pp. 189-191.