Enrichment of a fraction toxic to guinea-pigs from Pachystigma pygmaeum (Schltr.) Robyns

Patterton, H.G.; Potgieter, D.J.J.; Verschoor, J.A. (Jan Adrianus), 1953-

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dc.contributor.author	Patterton, H.G.
dc.contributor.author	Potgieter, D.J.J.
dc.contributor.editor	Bigalke, R.D.
dc.contributor.upauthor	Verschoor, J.A. (Jan Adrianus), 1953-
dc.date.accessioned	2015-04-02T06:55:29Z
dc.date.available	2015-04-02T06:55:29Z
dc.date.created	2014
dc.date.issued	1985
dc.description	The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.	en_ZA
dc.description.abstract	Pachystigma pygmaeum is one of several species of rubiaceous plants which cause delayed heart failure among ruminants after their ingestion at relatively high doses. Using guinea-pigs for toxicity determinations, we were able to separate and enrich a toxic fraction from a fermentation extract of the plant material by countercurrent distribution. It contained virtually no potassium salts, passed through a 500 dalton selective membrane, exhibited lability under acid conditions and was toxic at 1 g/kg per os, with a delayed response of 3-4 days.	en_ZA
dc.description.sponsorship	Department of Agriculture.	en_ZA
dc.identifier.citation	Verschoor, JA, Patterton, HG & Potgieter, DJJ 1985, 'Enrichment of a fraction toxic to guinea-pigs from Pachystigma pygmaeum (Schltr.) Robyns’, Onderstepoort Journal of Veterinary Research, vol. 52, no. 2, pp. 101-104.	en_ZA
dc.identifier.issn	0330-2465
dc.identifier.uri	http://hdl.handle.net/2263/44234
dc.language.iso	en	en_ZA
dc.publisher	Published by The Government Printer, Pretoria	en_ZA
dc.rights	©ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). ©University of Pretoria. Dept. of Library Services (digital).	en_ZA
dc.subject	Veterinary medicine	en_ZA
dc.subject.lcsh	Veterinary medicine -- South Africa
dc.title	Enrichment of a fraction toxic to guinea-pigs from Pachystigma pygmaeum (Schltr.) Robyns	en_ZA
dc.type	Article	en_ZA